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(4)
By Target- CaMK
- ROCK(1)
- Serine/threonin kinase(1)
- Others(2)
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Results for "
camkiiα
" in TargetMol Product Catalog- Inhibitors & Agonists8
- PROTAC Products1
CaMKIIα-PHOTAC
T79718
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+ calmodulin-dependent protein kinase II α (CaMKIIα), facilitating its ubiquitination and subsequent proteasome-mediated degradation when exposed to specific light wavelengths. Under illumination, CaMKIIα-PHOTAC diminishes synaptic functions and weakens evoked field excitatory postsynaptic potentials in the mouse hippocampus, impacting physiological responses and sustaining long-term potentiation and memory functions within dendritic domains [1].
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