Vitis

Procyanidin B1, isolated from commonly eaten fruits, binds to the TLR4/MD-2 complex and has anti-inflammatory activity.

Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression of AP-1 pathway.

Procyanidin C1 is a natural polyphenol that causes DNA damage, cell cycle arrest, and apoptosis induction. It reduces Bcl-2 protein levels and enhances the expression of BAX, caspase 3, and 9 in cancer cells.

Cyanidin Chloride, the main phenolic antioxidant in the grape (Vitis vinifera), in particular in the liposomal forms, could be used for treatment of diabetes mellitus complications.

Miquelianin (Quercetin 3-glucuronide) is a potent stilbene oxidase inhibitor, it has antioxidant, anti-atherogenic, and anti-inflammatory activities.

Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important medicinal properties.

Procyanidin B3(B3) is a procyanidin dimer that is widely studied due to its high abundance in the human diet and antioxidant activity.

Epifriedelanol (Epifriedelinol) suppresses adriamycin-induced cellular senescence, replicative senescence in human fibroblasts (HDFs) and HUVECs. Because of Epifriedelanol can reduce cellular senescence in human primary cells, it may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases.

(-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway

Atraric acid derivatives as a new chemical lead structure for novel therapeutic compounds as AR antagonists, that can be used for prophylaxis or treatment of prostatic diseases. It inhibits PTP1B activity in a dose-dependent manner with IC50 values of 51.5 uM, suggest that atraric acid has potential to treat diabetes.

2-Isobutyl-3-methoxypyrazine (3-Isobutyl-2-methoxypyrazine) is a RIFM fragrance commonly used in the food and cosmetic industries.

Diethyl malonate is naturally occurring in grapes and strawberries.

Nonanal is a growth factor for wood-rotting fungi. Nonanal is a potential attractant for the pine shoot beetle.

2-Phenylethyl Acetate is an Ebola virus inhibitor and can be used in biochemical experiments and drug synthesis.

(+)-Hopeaphenol is isolated from A. indica (L.) and V. indica Linn with an IC50 value of 21.21 μM in α-glucosidase inhibition assay.

Vitisin A ((+)-Vitisin A) is a resveratrol tetramer that can be isolated from the roots of Vitis vinifera and possesses antioxidant, anticancer, antiapoptotic, neuroprotective, and anti-inflammatory activities.It ameliorates the impaired learning and memory functions of scopolamine-induced amnesia in ICR mice, and can be used in the study of degenerative diseases.

Viniferol D is a natural product from Vitis vinifera.

4-[2-(3,5-Dimethoxyphenyl)ethyl]phenyl 6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside showed cytotoxic activities to Hela and hep2 cell lines.

Isopentylamine is a primary aliphatic amine that is structurally defined as butan-1-amine carrying a methyl substituent at the 3-position. Isopentylamine has documented biological role as both a plant metabolite and a bacterial metabolite, with additional potential applications being explored in the field of medical research.

cis-Miyabenol C exhibits antioxidative activities and shows strong hyaluronidase inhibitory effects. cis-Miyabenol C also has ecdysteroid antagonist activity.

Pinostilbenoside is a natural product of Vitis, Vitaceae. The catalog number is TN5643 and the CAS number is 58762-96-2. Pinostilbenoside can be used as a reference standard.

3-Methyl-2-butanol is an organic chemical compound classified as a secondary alcohol that is used industrially as a solvent and as a key synthetic intermediate in the manufacture of a diverse range of other chemicals. 3-Methyl-2-butanol has been investigated for potential applications as a reagent or solvent in various medical research contexts.

Procyanidin B4 reveals significant antioxidant activity

Astringin (trans-Astringin) is an orally active natural flavonoid that mitigates oxidative stress and inflammatory responses by inhibiting the PI3K/AKT/NF-κB pathway. It also modulates TLR4/MyD88, HMGB1/RAGE, and NF-κB pathways to counteract chromium-induced nephrotoxicity, whilst inhibiting ferroptosis.