Trachelospermum

Trachelogenin ((-)-Trachelogenin), isolated from Combretum fruticosum, is an HCV entry inhibitor with anti-proliferative effects. Its mechanism is related to affecting the phosphorylation of key proteins such as β-Catenin, c-Myc and GSK3 in the β-Catenin signaling pathway. chemical and concentration-dependent. Trachelogenin has antiviral, anti-inflammatory and analgesic activities with IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively.

Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml).

Nortrachelogenin-8'-O-beta-glucoside is a lignan with a diarylhydroxybutyrolactone skeleton which isolated from the leaves and stems of Trachelospermum jasminoides (Lindl.) Lem.

Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl asparagin-dependent apoptosis.

Arctigenin 4'-O-beta-gentiobioside is a natural product from Trachelospermum jasminoides.

Nortracheloside is one of the five lignan extracts present in Trachelospermi Caulis and Carissa edulis, with Trachelospermi caulis widely utilized in to alleviate fever and pain.Nortracheloside has been recognized as an active component capable of reducing allergen permeation and enhancing intestinal barrier function, thereby demonstrating promising potential to attenuate food allergy and inflammatory bowel disease through immunoregulatory bioactivity.

Suavissimoside R1 is a natural product isolated from Rubus parvifolius, suitable for biochemical experiments and drug synthesis research.

Nortrachelogenin-5'-C-beta-glucoside is a natural product of Trachelospermum, Apocynaceae. The catalog number is TN6509 and the CAS number is 858127-39-6. Nortrachelogenin-5'-C-beta-glucoside can be used as a reference standard.

Trachelosiaside shows moderate activity against lipoxygenase.