Cornaceae

Cephaeline was highly active against protected primary CLL cells (relative IC50's 35nM ) and acted by repressing HIF-1α± and disturbing intracellular redox homeostasis.

Evodiamine (d-Evodiamine) is an alkaloid isolated from the fruit of daylily and has a variety of biological activities including anti-inflammatory, anti-obesity and anti-tumor.

1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardial I/R and protect the liver from CCl4-induced acute hepatotoxicity, by reducing oxidative stress and suppressing inflammatory responses. 4. Cornuside has anti-inflammatory activity by downregulations of iNOS and COX-2 due to NF-κB inhibition as well as the negative regulation of ERK1/2, p38, and JNK1/2 phosphorylations in RAW 264.7 cells. 5. Cornuside has protective potential against cerebral ischemic injury, may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity, and improvements in mitochondrial energy metabolism and antioxidant properties.

Verbenalin (Verbenaloside) induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.

Rutaecarpine (Rhetine) is an inhibitor of COX-2 with IC50 of 0.28 μM.

Cephaeline dihydrochloride is a naturally occurring alkaloid that is a selective CYP2D6 inhibitor with an IC50=121 μM. It has an affinity for and oral activity at the 5-HT4 receptor and is capable of inducing vomiting.

Benzyl salicylate (NSC 6647), a salicylic acid derivative, is protective against cisplatin-induced apoptosis in LLC-PK1 cells and also inhibits LPS-induced NO production.

Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV.

Henryoside is a natural product isolated from the herbs of Alangium chinense.

(S,E)-Deca-2,9-diene-4,6-diyne-1,8-diol is a natural from Toricellia angulata

Ursolic aldehyde can inhibit phosphatase of regenerating liver-3, with the IC(50) value of 50 +/- 0.3 mu M.

3-Hydroxymethylcyclopentanone is a precursor to synthesize methyl epijasmonate. 3-Hydroxymethylcyclopentanone compounds, which are useful as intermediates in the preparation of HIV chemokine CCR-5 receptor antagonists.

Griselinoside is a natural product of Toricellia, Toricelliaceae. The catalog number is TN4170 and the CAS number is 71035-06-8. Griselinoside can be used as a reference standard.

Scholaricine reverses multidrug resistance in vincristine-resistant KB cells.

Deoxyflindissone exhibits significant cytotoxic activity against the A549, SK-OV-3, SK-MEL-2, and XF498 cell lines.

6-(beta-D-glucopyranosyloxy)-Salicylic acid methyl ester is a natural product. The catalog number is TN3155 and the CAS number is 108124-75-0. 6-(beta-D-glucopyranosyloxy)-Salicylic acid methyl ester can be used as a reference standard.

1,6-Dioxaspiro[4.5]decan-2-methanol is a natural product for research related to life sciences. The catalog number is TN2510 and the CAS number is 83015-88-7.

(R,E)-Deca-2-ene-4,6-diyne-1,8-diol is a natural from Toricellia angulata

Phyllostadimer A can significantly inhibit liposomal lipid peroxidation.