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Nucleosides and Nucleotides

Nucleosides and Nucleotides are key building blocks for RNA and DNA synthesis. Nitrogenous bases (purines or pyrimidines) first bind to pentose sugars (ribose or deoxyribose) to form nucleosides. These nucleosides undergo phosphorylation to generate nucleotides containing one to three phosphate groups. Nucleosides and Nucleotides participate in the encoding, transmission, and expression of genetic information, playing central roles in diverse physiological processes including cellular energy metabolism, signal transduction, and antioxidant defense. TargetMol offers high-quality and diverse nucleoside and nucleotide products to help you efficiently advance your life science research.

8-Azido-ATP trisodium
8-N3-ATP trisodium, 8-Azidoadenosine 5'-triphosphate trisodium
TNU1681
8-Azido-ATP (8-N3-ATP) trisodium is a photolabile nucleotide analog used for identifying proteins such as DNA-dependent RNA polymerase. As a click chemistry reagent, 8-Azido-ATP trisodium features an azide group that can engage in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.
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Cyclic GMP (TBAOH)
TNU1680
Cyclic GMP TBAOH is an endogenous second messenger that triggers the production of interferons in response to cytosolic DNA. It activates the stimulator of interferon genes (STING), initiating a signaling cascade that produces type I interferons and other immune mediators. The conjugate of Cyclic GMP TBAOH and AMP, known as Cyclic-GMP-AMP, can induce IRF3 phosphorylation and nuclear translocation to enhance antiviral immune responses. Additionally, Cyclic GMP TBAOH may activate PDE to degrade cAMP, inhibit the calcium current ICa in cardiomyocytes, and regulate myocardial contractility. Its derivative, 8-Br-cGMP, exhibits antiplatelet activity, making Cyclic GMP TBAOH useful for research in antiviral immunity and cardiovascular diseases.
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4'-C-azido-2'-deoxy-2'-fluorocytidine
TNU16781145869-35-7
4'-C-azido-2'-deoxy-2'-fluorocytidine can be synthesized under the combined action of N-methylimidazole, trimethyl phosphate and phosphorus oxychloride. The product can also be obtained with a yield of 72.6% by reacting in methanol as a solvent under the catalysis of p-toluic acid for 3.0 hours.
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7-Deaza-7-propargylamino-dATP TEA
TSW-01127
7-Deaza-7-propargylamino-dATP TEA is an analog of deoxyadenosine triphosphate (dATP) and is utilized in gene sequencing.
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3'-L-histidyl-AMP disodium
TSW-00974
3'-L-histidyl-AMP (disodium) is applicable for nucleotide modifications, including DNA and RNA.
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5-Iodo-dCTP
5-Iodo-2′-deoxycytidine 5′-triphosphate
TSW-0109431747-59-8
5-Iodo-dCTP serves as an excellent substrate for DNA polymerase and is utilized in DNA synthesis.
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10-14 weeks
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3'-O-Ac-dGTP sodium
TSW-01153
3'-O-Ac-dGTP sodium is an acetylated derivative of the nucleoside triphosphate 2'-deoxyguanosine-5'-triphosphate.
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3′-Amino-2′,3′-dideoxy-CTP
TSW-0112690053-17-1
3′-Amino-2′,3′-dideoxy-CTP is an analog of nucleoside triphosphates. It selectively inhibits DNA polymerase β.
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10-14 weeks
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Biotin-16-dGTP tetralithium
TCL-01253
Biotin-16-dGTP tetralithium is a biotin-labeled dGTP used for tagging oligonucleotides.
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dNTP Mixture
TSW-00956
dNTP Mixture, 25 mM Solution, PCR Grade is an equimolar blend of dATP, dGTP, dCTP, and dTTP, designed for use in biological amplification reactions, including PCR.
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LNA-AMP
TSW-009641092682-55-7
LNA-AMP is a nucleotide analog used in the synthesis of oligonucleotides.
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10-14 weeks
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2'-F-CDP
TSW-0095763555-61-3
2'-F-CDP is a nucleotide analog that can be utilized in the synthesis of oligonucleotides.
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10-14 weeks
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2'-O-MOE-GMP
TSW-009672305167-23-9
2'-O-MOE-GMP is a nucleotide analogue that can be utilized in the synthesis of oligonucleotides.
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10-14 weeks
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2'-Amino-2'deoxyadenosine-5'-O-diphosphate sodium
2'-NH2-ADP sodium
TSW-01128
2'-Amino-2'-deoxyadenosine-5'-O-diphosphate (2'-NH2-ADP) sodium is an amine-modified nucleotide, serving as a structural analog of the purine nucleotide ADP.
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3'-Bromo ANT-dGTP sodium salt
3'-O-(5-Bromoanthraniloyl)-2'-deoxyguanosine-5'-O-triphosphate sodium salt
TSW-01150
3'-Bromo ANT-dGTP [3'-O-(5-Bromoanthraniloyl)-2'-deoxyguanosine-5'-O-triphosphate] sodium is a derivative of dGTP.
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2'-O-MOE-UTP
TSW-00959847647-83-0
2'-O-MOE-UTP is a nucleotide analog employed in the synthesis of oligonucleotides.
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10-14 weeks
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N1-Methyl-2'-O-Methylpseudo-UTP
2'-O-Methylpseudouridine TP
TSW-010961613529-66-0
N1-Methyl-2'-O-Methylpseudo-UTP is a modified form of UTP used in RNA synthesis.
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10-14 weeks
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Sp-dUTPαS tetrasodium
TSW-01151
Sp-dUTPαS tetrasodium is an isomer of the sulfur-containing nucleotide dUTPαS.
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7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine
TNU1679
7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine is an analog of deoxyguanosine triphosphate (dGTP) commonly utilized in next-generation sequencing (NGS).
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3'-NH2-CTP
TSW-0110985708-23-2
3'-NH2-CTP is a nucleotide analog modified with an amino group at the 3' position of CTP.
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10-14 weeks
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3′-O-N3-dATP trisodium
3′-O-Azidomethyl dATP trisodium
TSW-00981
3′-O-N3-dATP trisodium (3′-O-Azidomethyl dATP trisodium) is the sodium salt form of 3′-O-N3-dATP. This compound is a modified nucleotide used for DNA polymerases. Acting as a reversible terminator, 3′-O-N3-dATP trisodium enhances Raman scattering (SERS) at 2125 cm-1, allowing for continuous DNA sequence analysis.
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3'-Amino-2',3'-dideoxy-TTP
TSW-0110790053-16-0
3'-Amino-2',3'-dideoxy-TTP is a derivative of thymidine triphosphate (TTP). It functions as a chain terminator in DNA synthesis.
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10-14 weeks
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7-Methylguanosine 5′-monophosphate
m7GMP, 7-Methylguanylic acid, 7-Methyl-GMP
TSW-0095110162-58-0
7-Methylguanosine 5′-monophosphate (7-Methylguanylic acid) is a component of nucleic acids.
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10-14 weeks
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Cyanine 3-dCTP
Cyanine 3-6-propargylamino-2'-deoxycytidine-5'-triphosphate
TSW-010932365531-97-9
Cyanine 3-dCTP is a nucleotide labeled with Cy3, used for DNA synthesis.
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