T5317 |
Cridanimod
|
38609-97-1
|
98%
|
|
Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/...
|
T36983 |
Cyclic-di-GMP disodium
|
2222132-40-1
|
98%
|
|
Cyclic-di-GMP disodium is a bacterial second messenger and a STING agonist involved in a variety of prokaryotic processes including biofilm formation, motility, ...
|
T11035 |
DiABZI STING agonist-1 (Tautomerism)
|
2138498-18-5
|
98%
|
|
diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respe...
|
T60000 |
2H-1,4-Benzothiazine-6-carboxamide, 4-[(2-chloro-6-fluorophenyl)methyl]-3,4-dihydro-3-oxo-N-(phenylmethyl)-
|
702662-64-4
|
98%
|
|
2H-1,4-Benzothiazine-6-carboxamide, 4-[(2-chloro-6-fluorophenyl)methyl]-3,4-dihydro-3-oxo-N-(phenylmethyl)- is a STING modulator with antibacterial and antiviral...
|
T5674 |
H-151
|
941987-60-6
|
98%
|
|
H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation.
|
T9204 |
N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide
|
727699-84-5
|
98%
|
|
N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide was reported as a STING inhbiitor, which inhibited the activation of the STING signal pat...
|
T5154 |
C-176
|
314054-00-7
|
98%
|
|
C-176 is a strong, covalent mouse STING inhibitor
|
T9028 |
STING-IN-2
|
346691-38-1
|
98%
|
|
C-170 is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflam...
|
T8328 |
STING agonist-1
|
702662-50-8
|
98%
|
|
STING agonist-1 is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
|
T6919 |
Omaveloxolone
|
1474034-05-3
|
98%
|
|
Omaveloxolone (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
|
T8655 |
SR-717
|
2375421-09-1
|
98%
|
|
SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. Antitumor acti...
|
T7081 |
CCCP
|
555-60-2
|
98%
|
|
CCCP inhibits activation of STING and its downstream signalling molecules, TBK1 and IRF3. CCCP inhibits STING-mediated IFN-β production via disrupting mitochondr...
|
T9029 |
STING-IN-3
|
2244881-69-2
|
98%
|
|
C-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation...
|
T9137 |
SN-011
|
2249435-90-1
|
98%
|
|
GUN35901 is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING- mediated disease. It is a demethyl ana...
|
T7329 |
C-178
|
329198-87-0
|
98%
|
|
C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells...
|
T8798 |
MSA-2
|
129425-81-6
|
98%
|
|
MSA-2 is a potent and orally available non-nucleotide STING agonist.
|
T9554 |
SN-008
|
2249106-01-0
|
98%
|
|
SN-008 is a less active analog SN-011 which is a STING antagonist. SN-008 can be used as a negative control.
|
T5516 |
DiABZI STING agonist-1 trihydrochloride
|
2138299-34-8
|
98%
|
|
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.
|
T13015 |
STING agonist-4
|
2138300-40-8
|
98%
|
|
STING agonist-4 is an agonist of stimulator of Interferon Genes (STING) receptor(IC50 of 20 nM).
|
T13613 |
ChX710
|
2438721-44-7
|
98%
|
|
ChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequenc...
|