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Results for "

tyro-3

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    7
    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
    11
    TargetMol | Recombinant_Protein
  • Antibody Products
    2
    TargetMol | Antibody_Products
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Dtk Protein, Human, Recombinant (His)
Tyrosine-protein kinase TIF, Tyrosine-protein kinase SKY, Tyrosine-protein kinase RSE, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, Tyrosine-protein kinase BYK, TYRO3, TIF, SKY, RSE, DTK, BYK
TMPJ-01081
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to the anticoagulation factor protein S. The binding affinities for Gas6 is in the order of Axl > Dtk > Mer. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Dtk is widely expressed during embryonic development. In adults, Dtk is predominantly expressed in neurons in restricted regions of the brain.
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7-10 days
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SPR-compatible buffer
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TYRO3 Protein, Cynomolgus, Recombinant (His)
TYRO3, TIF, SKY, Rse, DTK, BYK, Brt
TMPK-00533
TYRO3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.47 kDa and the accession number is A0A2K5WCY8.
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7-10 days
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SPR-compatible buffer
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TYRO3 Protein, Mouse, Recombinant (His)
TYRO3, TIF, SKY, Rse, DTK, BYK, Brt
TMPK-00901
TYRO3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 43 kDa and the accession number is P55144-2.
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7-10 days
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SPR-compatible buffer
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Dtk Protein, Mouse, Recombinant (hFc)
Tyrosine-protein kinase TIF, Tyrosine-protein kinase RSE, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, tyro3, TK19-2, Etk2
TMPJ-01017
Dtk Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P55144.
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7-10 days
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SPR-compatible buffer
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Dtk Protein, Mouse, Recombinant (mFc)
Tyrosine-protein kinase TIF, Tyrosine-protein kinase RSE, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, Tyro3, TK19-2, Etk2 tyro3
TMPJ-01018
Dtk Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number is P55144.
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7-10 days
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QTY
SPR-compatible buffer
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EPHB2 Protein, Cynomolgus, Recombinant (His)
TYRO5, Sek3, Qek2, PCBC, Nuk, HEK5, ERK, EPHT3MGC87492, EPHT3, EphB2, EK5, DRT, Cek5, CAPB
TMPK-00563
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia.
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7-10 days
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SPR-compatible buffer
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EphB3 Protein, Human, Recombinant (His)
TYRO6, Sek4, MDK5, HEK2, ETK2, EPHB3, EK2, EC 2.7.10.1, EC 2.7.10, Cek10, AW456895
TMPK-00898
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is contributed to downregulation of EphB3 in CRC. EphB3 expression in tumor cells may be a useful prognostic indicator for patients with CRC.
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7-10 days
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EPhA3 Protein, Canine, Recombinant (His)
TYRO4, HEK4, HEK, ETK1, ETK, EPHA3, EK4
TMPK-01387
Erythropoietin‑producing hepatocellular carcinoma cell surface type‑A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (‑295~‑261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.
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7-10 days
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SPR-compatible buffer
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DDR2 Protein, Human, Recombinant (hFc)
TYRO10, TKT, NTRKR3, MIG20a, discoidin domain receptor tyrosine kinase 2, CD167
TMPY-00773
Expression system: HEK293 Cells
Length: 1-399, Partial
Activity: Not Tested
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7-10 days
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QTY
SPR-compatible buffer
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DDR2 Protein, Human, Recombinant (His)
TYRO10, TKT, NTRKR3, MIG20a, discoidin domain receptor tyrosine kinase 2, CD167
TMPY-03625
Expression system: HEK293 Cells
Length: 1-399, Partial
Activity: Not Tested
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7-10 days
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SPR-compatible buffer
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DDR2 Protein, Human, Recombinant (aa 422-855, His & GST)
TYRO10, TKT, NTRKR3, MIG20a, discoidin domain receptor tyrosine kinase 2, CD167
TMPY-04361
Expression system: Baculovirus Insect Cells
Length: 422-855, Partial
Activity: Enzyme activity
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7-10 days
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QTY