tame

TAME (Tosyl-Arginine Methyl Este), an inhibitor of the late-promoting complex (APC C or APC), inhibits APC-dependent protein hydrolysis by competing for APC binding with the C-terminal isoleucine-arginine tail of the APC activator cytokinesis cycle 20 (Cdc20). TAME binds to and prevents APC binding by Cdc20 and Cdh20. TAME binds to APC and prevents its activation by Cdc20 and Cdh1.

TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.

ProTAME is an inhibitor of APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, doxorubicin and etoposide, significantly increase cell death in primary cells and Multiple Myeloma (MM) cell lines, particularly if TOPIIα levels are first increased through pre-treatment with ProTAME.This compound is unstable in powder form and other related salt forms are recommended.

Cefetamet sodium (Ro 15-8074 001) is an orally available cephalosporin antibiotic with antimicrobial activity and is used to study cirrhosis of the liver and lung infections.

RU 47213 can be used to inhibit scopolamine-induced working memory impairment in rats.

Itameline (RU 47213) can be used as a choline mimetic.

Aspartame (SC-18862), an artificial, non-carbohydrate sweetener, is aspartyl-phenylalanine-1-methyl ester.

2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the antioxidant component of vitamin E (α-tocopherol) and exhibits significant androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.

Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate (SCH 11460) binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, control of malaria and other vector-borne diseases. It is easily degradable.

Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a corticosteroid with anti-inflammatory properties that promotes the polarization of M1 to M2 macrophages by reducing the secretion of pro-inflammatory cytokines, and is utilized in research on keloids and rheumatoid arthritis.

Neotame (HSDB 7965) is a white-colored, dipeptide methyl ester, which is found to be a highly potent and non-nutritive sweetener or flavour enhancer and hence finds applications in a variety of foods.

Cefetamet pivoxil hydrochloride (Ro 15-8075) is a third generation cephalosporin antibiotic with oral activity.

Betamethasone valerate (Luxiq) is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions.

Pentamethylene bisacetamide is a useful organic compound for research related to life sciences. The catalog number is T125825 and the CAS number is 146695-99-0.

1,2,3,4,7-Pentamethoxy-9H-xanthen-9-one is a useful organic compound for research related to life sciences and the catalog number is T125893.

5,6,7,3',4'-Pentamethoxyflavanone is a useful organic compound for research related to life sciences and the catalog number is T126486.

Betamethasone-17-butyrate-21-propionate is a topical corticosteroid used to treat inflammatory skin diseases.

Betamethasone acibutate, a glucocorticoid, is derived from Betamethasone.

Betamethasone 17-benzoate, a representative steroid, is used in the treatment of recurrent aphthous ulcers (RAU).

Betamethasone (NSC-39470), a glucocorticoid steroid, has immunosuppressive and anti-inflammatory properties.

3',4',5',5,7-Pentamethoxyflavanone is a natural flavonoid compound found in [Neoraptua magnifica var. magnifica].

Betamethasone 17-Propionate is a compound used in the study of its effects on endotoxin-induced uveitis in rats, capable of inhibiting cellular infiltration into the aqueous humor when administered topically or systemically at certain doses. However, compared to some other compounds, its inhibitory effects are relatively weaker. When administered systemically, the dosage is 1mg kg. Additionally, in in vitro interleukin-8 (IL-8) release assays, Betamethasone 17-Propionate's suppression of IL-8 release from rat peritoneal exudate cells is less effective than that of betamethasone. Moreover, the concurrent addition of betamethasone dipropionate with Betamethasone 17-Propionate reduces the suppressive effects of betamethasone on cell infiltration and IL-1β gene expression.

Betamethasone 21-valerate is a corticosteroid ester with anti-inflammatory properties.