stem bark

(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid displays EC50 values of 73.5 μM against T. cruzi. trypomastigotes.

4-Isopropylbenzoic acid (Cumic acid) is an aromatic monoterpenoid isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid shows antifungal activities. 4-Isopropylbenzoic acid is also a reversible and uncompetitive mushroom tyrosinase inhibitor.

Pinoresinol dimethyl ether is a nonphenolic furan lignan isolated from the stem bark of Magnolia kobus with neurological activity. It stimulates upstream MAPK, PKC and PKA pathways and induces neural protrusion growth in PC12 cells.

Mahanimbidine, a terpenoid alkaloid, is extractable from the leaves and stem bark of Murraya koenigii Spreng [1] [2].

Erythrodiol diacetate (Compound 4) is a triterpenoid derived from the stem bark of *Erythrina eriotriocha* [1].

Chisocheton compound F, a natural product, can be isolated from the stem bark of Melia toosendan [1].

Pinoresinol dimethyl ether (Standard) is a reference standard for research and analysis in studies involving Pinoresinol dimethyl ether. Pinoresinol dimethyl ether is a nonphenolic furan lignan isolated from the stem bark of Magnolia kobus with neurological activity. It stimulates upstream MAPK, PKC and PKA pathways and induces neural protrusion growth in PC12 cells.

4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of Ailanthus altissima. Additionally, five other known compounds were identified. The structure of the new compound was established through analysis of physical and spectral data, and its absolute configuration was determined using electronic circular dichroism and quantum chemical calculations. These compounds exhibit significant inhibitory activity on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, indicating potential anti-inflammatory properties.

Styraxlignolide G is a furan-type lignan compound that can be isolated from the stem bark of Styrax japonicus. It exhibits very weak DPPH radical-scavenging activity, but the aglycone produced by hydrolysis shows antioxidant activity (IC50=186.7 μM) and is involved in oxidative stress regulation. Styraxlignolide G can be utilized in the study of inflammatory diseases.

Trichilin H is a limonoid compound found in the stem bark of Melia toosendan. It exhibits antifeedant activity against third instar larvae of the southern armyworm (Spodoptera litura).

Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammatory cytokine secretion and can be used in studies about the prevention and treatment of inflammatory diseases, type-2 diabetes, obesity and metabolic syndrome.

Cotoin, a natural product isolated from the stem bark of Garcinia virgate, exhibits antispasmodic activity by reducing the tone and contraction of isolated rabbit intestine. It partially inhibits the effects of acetylcholine, trichothecenes, and BaCl on the isolated intestine.

Evofolin B is a natural compound isolated from the stem bark of Zanthoxylum ailanthoides. Evofolin B has an inhibitory effect on the superoxide anion produced by human neutrophils in response to formyl-L-methionine-L-leucine-L-phenylalanine/cytochalasin B (fMLP/CB).

3-Hydroxy-4',5-dimethoxystilbene is a natural compound found in stem bark of Morus nigra L. 3-Hydroxy-4',5-dimethoxystilbene is therefore utilized in phytochemical and natural product profiling studies for structural characterization of stilbene derivatives in Morus nigra L. biosystems. 3-Hydroxy-4',5-dimethoxystilbene is also applied in biochemical screening workflows investigating stilbene scaffold diversity and plant secondary metabolite mapping.

4'-O-Methyllicoflavanone is isolated from the stem bark of Erythrina orientalis and shows antioxidant activity against DPPH radical with an IC50 value of 648.1 μM.

Abyssinone V is a natural compound isolated from the stem bark of Erythrina melanacantha and an inhibitor of protein tyrosine phosphatase-1B (PTP1B).

Matairesinoside is a lignan extracted from the stem bark of Styrax japonica S. et Z, which is known to exhibit antibacterial and antioxidant properties while also functioning as a virus–cell fusion inhibitor. Matairesinoside acts as a potent inhibitor of TMEM16A, a novel target implicated in lung cancer progression, confirmed through molecular simulation and site-directed mutagenesis. Matairesinoside significantly reduces lung cancer cell growth, migration, and invasion while inducing apoptosis, with gene knockdown and overexpression demonstrating TMEM16A as the direct target and Western blot analysis elucidating the associated signaling pathways involved in tumor suppression.

Salaspermic acid, a triterpenoid isolated from the stem bark of Kokoona ochracea, is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocytes, and can be used to study HIV infection.

N-Formylcytisine ((-)-N-Formylcytisine) is a natural product isolated from the stem bark of Maackia amurensis.

Alashinol G ((-)-Carinol) is isolated from the stem bark of Syringa pinnatifolia, a Mongolian folk medicine with anti-myocardial ischaemic effects.

Magnoloside F is a natural product found in the stem bark of Magnolia officinalis.

3β-Acetoxyurs-12-en-11-one (11-Ketoamyrinacetate) is an ursane triterpene natural product present in the stem bark of Morus mesozygia and the leaves of Ficus hirta Vahl (Moraceae).

2,5-Dihydroxy-7-methoxyflavanone, a flavonoid compound, can be isolated from the stem bark of F. enghiana [1].

Sitosterone, a steroid isolated from the stem bark of Syzygium aqueum, exhibits cytotoxic properties.