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20

Compounds

Cat No. Product Name Synonyms Targets
T9519 Eliapixant BAY 1817080 P2X Receptor
Eliapixant (BAY 1817080) (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.
T12367 Parsaclisib INCB050465 PI3K
Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 mM ATP)
T20759 XRP44X XRP-44-X,XRP 44X,XRP-44X,XRP 44 X Ras
XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.
T28297 Parsaclisib hydrochloride Parsaclisib HCl,INCB-50465,INCB 050465,INCB-050465,INCB050465 HCl,INCB 50465,INCB50465 HCl PI3K
Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity with IC50 values ranging from 0.2 to 2 nM.
T21444 Diphenylcyclopropenone DPCP,Diphencyprone Others
Diphenylcyclopropenone (DPCP) is a topical drug used to treat alopecia areata, alopecia totalis, and refractory warts. Diphencyprone acts as a local stimulator that triggers an immune response against the action of autor...
T76692 Mosunetuzumab BTCT-4465A Others
Mosunetuzumab (BCT-4465A) is a humanized antibody based on immunoglobulin G1 that targets CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used to stu...
T3078 SGI-1776 SGI-1776 free base,Pim-Kinase Inhibitor IX Apoptosis , FLT , Pim , Autophagy
SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.
T71973 Gilteritinib hemifumarate ASP2215 hemifumarate FLT , TAM Receptor
Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of relapsed or refractory FLT3 mutant AML.
T76718 Brentuximab TNF
Brentuximab is a chimeric antibody targeting CD30 and is a naked antibody to Brentuximab vedotin.Brentuximab has antitumor activity and may be used to study relapsed or refractory Hodgkin's lymphoma.
T76927 Bersanlimab BI-505 Integrin
Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties and can be used to study relapsed/refractory multiple myeloma.
T77750 Rosmantuzumab OMP-131R10 Others
Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3). Rosmantuzumab has potential antitumor activity and can be used to study advanced relapsed refractory solid tumors.
T4869 D-Allose β-D-Allopyranose,D-(+)-ALLOSE Others , Endogenous Metabolite
D-Allose (β-D-Allopyranose) is a rare naturally occurring monosaccharide known to exert anti-proliferative effects on cancer cells. The effects of D-Allose on the cellular membranes of hormone-refractory prostate cancer ...
T76685 Glofitamab RO7082859,RG 6026,CD20-TCB Others
Glofitamab (RO7082859) is a novel bivalent antibody directed against CD20-binding T cells.Glofitamab promotes T cell proliferation and activation and tumor cell killing by binding to CD20 on malignant cells.Glofitamab ca...
T77909 Mirzotamab
Mirzotamab, an IgG1κ antibody, targets CD276/B7-H3 and conjugates with Clezutoclax, a BCL-2 inhibitor, to create Mirzotamab clezutoclax. This antibody-drug conjugate (ADC), identified as ABBV-155, is currently under inve...
T12660L BAY1238097 Epigenetic Reader Domain
BAY1238097 is a potent and selective bromodomain and extra-terminal motif (BET) inhibitor with anticancer activity that exhibits strong antiproliferative activity in AML (Acute Myeloid Leukemia) and MM (Multiple Myeloma)...
T6541 Ibutilide Fumarate Corvert Fumarate,U70226E Calcium Channel , Sodium Channel
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outwar...
T9969 EZM0414 Histone Methyltransferase
EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 with IC50 of 18 nM in SETD2 biochemical assay and IC50 of 34 nM in a cellular assay. EZM0414 can be used for the research of relapsed or refractory m...
T6476 Dofetilide UK 68789,UK-68798,Tikosyn Potassium Channel
Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ik...
T15257 Etripamil MSP-2017,(-)-MSP-2017 Calcium Channel
Etripamil (MSP-2017) displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells...
T6S0735 Flavokawain B Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone Apoptosis , Others
1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, in...
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