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Ersodetug
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Catalog No. T9901A-1529Cas No. 2410976-61-1
Alias XOMA 358, RZ-358
Ersodetug (RZ358) is a fully human monoclonal antibody that targets an allosteric site on the insulin receptor (IR). As a negative modulator of insulin receptor activity, it effectively counteracts refractory hypoglycemia caused by insulin oversecretion, demonstrating significant potential in the study of congenital hyperinsulinism.
Ersodetug
Ersodetug
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Catalog No. T9901A-1529Alias XOMA 358, RZ-358Cas No. 2410976-61-1
Ersodetug (RZ358) is a fully human monoclonal antibody that targets an allosteric site on the insulin receptor (IR). As a negative modulator of insulin receptor activity, it effectively counteracts refractory hypoglycemia caused by insulin oversecretion, demonstrating significant potential in the study of congenital hyperinsulinism.
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| Description | Ersodetug (RZ358) is a fully human monoclonal antibody that targets an allosteric site on the insulin receptor (IR). As a negative modulator of insulin receptor activity, it effectively counteracts refractory hypoglycemia caused by insulin oversecretion, demonstrating significant potential in the study of congenital hyperinsulinism. |
| Synonyms | XOMA 358, RZ-358 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | INSR |
| Cas No. | 2410976-61-1 |
| Isotype | IgG2SA-TM |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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