r 33

TPT-172, also known as R33 (described in Mecozzi et al' s paper), is a thiophene thiourea derivative with molecule weight 172 in free base form. There is no formal name yet, we temporally call this molecule as TPT-172. Please also see similar products: TP

GLP-1R agonist 33 (Compound 224) is a GLP-1 receptor agonist with potential applications in research related to diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD).

The compound (3R,21Z,24Z,27Z,30Z,33Z)-3-Hydroxyhexatriacontapentaenoyl-CoA ((3R,21Z,24Z,27Z,30Z,33Z)-3-Hydroxyhexatriacontapentaenoyl-coenzyme A) is an unsaturated acyl-CoA.

(3R,18Z,21Z,24Z,27Z,30Z,33Z)-3-Hydroxyhexatriacontahexaenoyl-CoA ((3R,18Z,21Z,24Z,27Z,30Z,33Z)-3-Hydroxyhexatriacontahexaenoyl-coenzyme A) is an unsaturated acyl-coenzyme A.

Apoptosisinducer 33 (compound H2) is a hydrazone derivative. It exhibits antioxidant and antimicrobial properties, capable of inhibiting the growth of Staphylococcus aureus, Escherichia coli, and Candida albicans. Additionally, Apoptosisinducer 33 can suppress tumor cell proliferation and induce apoptosis (apoptosis), making it useful for tumor research.

Carbonic anhydrase inhibitor33 (11D) is a dual inhibitor that targets both CA (carbonic anhydrase) IX/XII and CDK6. It exhibits Ki values of 19.7 nM for hCA IX and 26.1 nM for hCA XII. Additionally, Carbonic anhydrase inhibitor33 (11D) can induce G1 phase cell cycle arrest and apoptosis, making it relevant for research in non-small cell lung cancer (NSCLC).

Menin-MLL inhibitor 33 (compound 15-a) is a potent Menin-MLL inhibitor, with an IC50 value of 3.6 nM, and exhibits antiproliferative activity.

Ca2+ channel antagonist

XR 334 is a biochemical.

KRAS G12C inhibitor 33 is a KRAS G12C inhibitor used in cancer research.

Tubulin Inhibitor 33 is a dose-dependent inhibitor of tubulin polymerization, exhibiting an IC50 value of 9.05 μM. This compound demonstrates antitumor activity and induces apoptosis, making it useful for antitumor research [1].

Poloxamer 333 P103 is a block copolymer of polyethylene oxide and polypropylene oxide with an average molecular weight of 4950. It exhibits antibacterial activity, inhibiting 90% of Mycobacterium avium at a concentration of 1 mg/mL. The compound forms a thermoreversible hydrogel and is used as a food additive, as well as a drug delivery carrier in cosmetics, pharmaceuticals, and tissue engineering.

Poloxamer 334 P104 is a block copolymer of polyoxyethylene and polyoxypropylene with an average molecular weight of 5900. It forms a thermoreversible hydrogel and is utilized as a food additive. Additionally, Poloxamer 334 P104 serves as a drug delivery vehicle in cosmetics, pharmaceuticals, and tissue engineering.

Poloxamer 335 P105 is a block copolymer composed of polyoxyethylene and polyoxypropylene, with an average molecular weight of 6500. At a concentration of 1 mg/mL, it exhibits antibacterial properties by inhibiting 86% of Mycobacterium avium. Meanwhile, Poloxamer 334 P104 has muscle toxicity and forms thermoreversible hydrogels, making it useful as a food additive and a drug delivery vehicle in cosmetics, pharmaceuticals, and tissue engineering.

Poloxamer 338 F108 is a block copolymer of polyoxyethylene and polyoxypropylene with an average molecular weight of 14,600. It is capable of reducing red blood cell aggregation and inhibiting the proliferation of human lymphocytes IIBR1. In rats, Poloxamer 338 F108 exhibits short-term and subchronic toxicity.

SR-3306 is a brain-penetrant and selective pan-JNK (JNK1/2/3) inhibitor with IC50 values ​​of 67 nM, 283 nM, 159 nM, respectively, and reduces food intake and body weight.

Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.

Salmeterol Xinafoate (GR 33343X xinafoate) is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms.

SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)

Roxoperone is a bioactive chemical.

Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which - among others - regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and rhomboid fossa).

Pipamperone (McN-JR 3345) binds 5-HT2A closely as receptor.

Salmeterol (GR33343X) is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.

(R)-Ofloxacin is a R-isomer of Ofloxacin, an antibiotic used to treat a number of bacterial infections.