piperazine

Piperazine (1,4-Diazacyclohexane), a gamma-aminobutyric acid (GABA) agonist, serves as a crucial building block and core component in a wide range of marketed drugs known for their varied pharmacological activities.

BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride, a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1) programmed cell death ligand 1 (PD-L1) inhibitor, inhibits the PD-1 PD-L1 interaction with an IC50 of 39.2 nM. It contains the target protein PD-1 PD-L1 ligand and PROTAC linker, which can be used to synthesize PROTAC PD-1 PD-L1 degrader-1 and has anticancer activity. Additionally, it serves as a diluent for the preparation of tablets for direct compression.

Sultosilic acid piperazine salt (A-585) is a novel lipid-lowering compound that can be used to study type IIb familial combined hyperlipidemia.

GNF-8625 monopyridin-N-piperazine hydrochloride is a tropomyosin receptor kinase (TRK) inhibitor.

Piperazine,1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]- is a piperazine derivative with anti-SARS-CoV-2 activity.

11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).

Piperazine adipate (Piperazine adipate) is a highly effective broad-spectrum anthelmintic that works by causing paralysis in parasitic worms.

Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmintic.

1-(2-Pyridyl)piperazine (NSC-13778) is a selective α2-adrenoceptor antagonists. 1-(2-Pyridyl)piperazine shows sympatholytic activity. 1-(2-Pyridyl)piperazine is also a metabolite of Azaperone.

Piperazine erastin, an analog of erastin, induces ferroptosis, an iron-dependent form of non-apoptotic cell death.

N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine is a biologically active compound belonging to the piperazine group. It is an important synthetic intermediate used in the preparation of a wide range of drugs, agrochemicals and other chemicals. It is considered an inhibitor of certain enzymes involved in drug metabolism, such as cytochrome P450 enzymes, and has also been shown to have anti-inflammatory and antitumor effects.

1-(Phenylsulfonyl)Piperazine Hydrochloride is a fragmetnt molecule that can be used in life science related research. The CAS number of 1-(Phenylsulfonyl)Piperazine Hydrochloride is 412293-98-2.

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) is a raw material for biosynthesis and can be used to synthesize various compounds.

1-[(5-methylisoxazol-3-yl)methyl]piperazine (Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]-) is a P2Y12 inhibitor.

1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple serotonin (5-HT) receptors.

1-(3-chloropyridin-2-yl)piperazine dihydrochloride is a piperazine analog often used as a reagent in organic synthesis, as a ligand in coordination chemistry, and as a drug in pharmaceuticals. It is an inhibitor of DPP4, and DPP4 inhibition has been shown to have beneficial effects in the treatment of certain diseases such as type 2 diabetes and obesity.

1-(1-phenyltetrazol-5-yl)piperazine;hydrochloride (1-(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)piperazine hydrochloride) is a chemical derivative of piperazine that has been used as a starting material for the synthesis of other compounds, such as anti-inflammatory agents. It modulates the activity of enzymes and proteins by binding to their active sites, and has been used in studies of enzyme inhibition and protein structure, as well as in drug metabolism.

1-BENZENESULFONYL-PIPERAZINE is a fragmetnt molecule that can be used in life science related research. The CAS number of 1-BENZENESULFONYL-PIPERAZINE is 14172-55-5.

Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine can be used to alter the lifespan of eukaryotic cells.

Thalidomide-Piperazine-Piperidine is a compound composed of a synthesized E3 ligase ligand-linker conjugate. It combines a cereblon ligand derived from Thalidomide with a linker commonly used in PROTAC technology.

Thalidomide-piperidine-CO-piperazine-C-3-Br-Ph is a type of E3 ubiquitin ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugates). It is utilized in the synthesis of PROTAC SMARCA2 degrader-28.

1-{1H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine dihydrochloride (1-PPZ-DHC) is a compound used as a molecular structural unit. It is an analog of the natural product piperazine and has a wide range of biological activities, including anti-inflammatory, anti-tumor and antibacterial activities. It has also been studied for the treatment of neurological disorders such as Alzheimer's and Parkinson's.

Aniline-piperazine-C3-NH-Boc (Compound Int-3) is a PROTAC linker utilized in the synthesis of Pomalidomide-C3-adavosertib and AZD1775 (a Wee1 inhibitor).

Lenalidomide-C13-piperazine-Boc is a conjugate of an E3 ligase ligand and linker used in synthesizing the PROTAC degrader NC-R17.