phenothiazine

Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis.

Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.

3-Amino-1-(2-chloro-10H-phenothiazin-10-yl)-1-propanone is involved in the synthesis of phenothiazine series compounds.

3-(4'-Carboxyphenyl)imino-3H-phenothiazine is a Bio-reagent, fine chemical.

3-(2',5'-Disulfophenylimino)-3H-phenothiazine is a Bio-reagent, fine chemical.

2-Methoxy Phenothiazine is light yellow or light gray solid.

2-Chlorophenothiazine is used as the intermediate of Chlorpromazine hydrochloride.

RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties. It exhibits considerable effectiveness against an EGFR-driven cancer xenograft model. The mechanism behind its efficacy can be attributed to the simultaneous inhibition of PI3K-AKT and RAS-ERK signaling pathways.

PPA-904, a specific phenothiazine photosensitizer, is used in photodynamic therapy (PDT).

Quisultazine is a phenothiazine derivative with no central effects, can be classified as a non anti H2 antisecretory agent.

Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metabolic process of this commonly used dopamine antagonist.

Prochlorperazine Maleate (Capazine) is a phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS.

Promazine hydrochloride (Romtiazin hydrochloride) is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.

Zuclopenthixol (cis-Clopenthixol) is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.

carfenazine targets the Dopamine receptor and is used for schizophrenia research.

Biperiden (Bipariden) is a muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.

Triflupromazine is a phenothiazine drug used as an antipsychotic and antiemetic.

Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family.

Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor.

Levomepromazine (Methotrimeprazine) is an orally active aliphatic phenothiazine antipsychotic compound and a Ca2+ release inducer, exhibiting antiviral, anti-inflammatory, neuroprotective, analgesic, and anti-nociceptive activities. Levomepromazine inhibits dopaminergic, cholinergic, serotoninergic, and histaminergic receptors, and is used for research in neurodegenerative diseases.

RTC-30, an optimized phenothiazine compound, possesses potent anti-cancer properties and is formulated with a hydroxylated linker (N) to enhance its oral bioavailability[1].

Perazine dimlonate, a compound belonging to the phenothiazine class, exhibits neuroleptic properties. It is primarily used to treat psychotic disorders.

Ethopropazine Hydrochloride is the salt form of Ethopropazine (Profenamine), a phenothiazine derivative with anticholinergic, antihistamine, and anti-adrenergic effects used in the treatment of Parkinson's disease, and acts as an AChE inhibitor by affecting the PAS active site.