phenothiazine

Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis.

3-Amino-1-(2-chloro-10H-phenothiazin-10-yl)-1-propanone is involved in the synthesis of phenothiazine series compounds.

3-(2',5'-Disulfophenylimino)-3H-phenothiazine is a Bio-reagent, fine chemical.

3-(4'-Carboxyphenyl)imino-3H-phenothiazine is a Bio-reagent, fine chemical.

Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.

2-Methoxy Phenothiazine is light yellow or light gray solid.

2-Chlorophenothiazine is used as the intermediate of Chlorpromazine hydrochloride.

PPA-904, a specific phenothiazine photosensitizer, is used in photodynamic therapy (PDT).

Quisultazine is a phenothiazine derivative with no central effects, can be classified as a non anti H2 antisecretory agent.

RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties. It exhibits considerable effectiveness against an EGFR-driven cancer xenograft model. The mechanism behind its efficacy can be attributed to the simultaneous inhibition of PI3K-AKT and RAS-ERK signaling pathways.

Zuclopenthixol (cis-Clopenthixol) is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metabolic process of this commonly used dopamine antagonist.

Prochlorperazine Maleate (Capazine) is a phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS.

Promazine hydrochloride (Romtiazin hydrochloride) is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.

Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.

carfenazine targets the Dopamine receptor and is used for schizophrenia research.

Opromazine hydrochloride belongs to the phenothiazine class of antipsychotics and reduces the activity of dopaminergic pathways by blocking dopamine receptors in the brain. It is mainly used for the treatment of psychiatric disorders such as schizophrenia and psychosis.

Triflupromazine is a phenothiazine drug used as an antipsychotic and antiemetic.

Dacemazine is a phenothiazine derivative that acts as a histamine antagonist at the H1 subtype. It was also assessed as a possible anticancer drug.

ProMazine-d6 hydrochloride is a deuterated compound of ProMazine hydrochloride. ProMazine hydrochloride has a CAS number of 53-60-1. Promazine hydrochloride is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.

Levomepromazine HCl is a phenothiazine with pharmacological activity similar to that of both CHLORPROMAZINE and PROMETHAZINE. It has the histamine-antagonist properties of the antihistamines together with CENTRAL NERVOUS SYSTEM effects resembling those of chlorpromazine.

alpha-Clopenthixol dihydrochloride is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

RTC-30, an optimized phenothiazine compound, possesses potent anti-cancer properties and is formulated with a hydroxylated linker (N) to enhance its oral bioavailability[1].

Perazine dimlonate, a compound belonging to the phenothiazine class, exhibits neuroleptic properties. It is primarily used to treat psychotic disorders.