olive

Oleuropeinic acid, initially present in olive tissues or produced through the thermal oxidation of oleuropein, is an antioxidant-soluble fiber.

Olivetolic acid (OLA) is a precursor of cannabinoids from Cannabis sativa and has shown anticonvulsant activity in a mouse model of Dravet syndrome.Olivetolic acid has potential antimicrobial activity.

Oliveroline is an alkaloid found in plants that demonstrates strong inhibition of Topo I and remarkable inhibition of Topo II, surpassing similar compounds such as topotecan and etoposide. The Topo I complexes it forms are more stable than those with Topo II, highlighting its potential as a promising candidate for further cancer treatment research.

Olivetol (5-n-Amylresorcinol) (5-pentylresorcinol, 5-pentyl-1,3-benzenediol) is an organic compound found in certain species of lichen; it is also a precursor in various syntheses of tetrahydrocannabinol. Olivetol has an antioxidant effect.

Olivetol Dimethyl Ether is a monoacylglycerol with analgesic activity and potential anti-inflammatory activity that inhibits fatty acid synthesis.

Homovanillyl alcohol, a biological metabolite of Hydroxytyrosol, is a phenolic compound found in virgin olive oil (VOO) and wine. It exhibits high scavenging activities, protects red blood cells from hemolysis in a dose-dependent manner, and has a protective effect on cardiovascular disease and total mortality.

4-Hydroxycyclohexanecarboxylic acid is a substrate of cyclohexanecarboxylic acid and is isolated from olive brine.

Hydroxytyrosol (2-(3,4-Di-hydroxyphenyl)-ethanol) is an active ingredient extracted from the olive. It is one of the most efficient and secure antioxidants and can be used in the cardiovascular drugs.

Hydroxytyrosol Acetate (HTy-Ac) is found in the olive oil with antioxidant activity.

Fucoxanthin (all-trans-Fucoxanthin) is a carotenoid naturally found in certain algae, serving as an accessory pigment in the chloroplasts of brown algae and most other heterokonts, which imparts a brown or olive-green color. It exhibits anti-obesity, antioxidant, anti-diabetic, anticancer, and anti-inflammatory activities.

Erythrodiol, an olive oil component, promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein.

Oleuropein is an antioxidant polyphenol isolated from olive leaf.

Uvaol is present in olives and virgin olive oil with anti-inflammatory, anti-proliferative, and vasorelaxant activities.

Hydroxytyrosol 4-O-glucoside (Hydroxytyrosol 4-beta-D-glucoside) is from olive fruits.

Cycloolivil (Isoolivil) is a natural polyphenolic compound found in olive trees that exhibits significant radical scavenging and antioxidant activities. It may prevent thrombotic complications associated with platelet hyperaggregability and serve as a foundational compound for further research.

6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transporter substrate, across Caco-2 cell monolayers (IC50 = 0.7 μM). 6'7'-Epoxybergamottin also has insecticidal properties with a concentration of 5 μg/cm2 leading to 100% mortality of adult olive fruit flies.

Urolithin M5 (Decarboxyellagic acid) is a neuraminidase inhibitor isolated from olive leaves with antiviral and anticancer and antitumor activities. Urolithin M5 can be used to study influenza A virus infection and SARS-CoV-2 infection.