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Results for "

nudt5

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
    1
    TargetMol | Recombinant_Protein
  • Antibody Products
    1
    TargetMol | Antibody_Products
TH5427
T39785L2253744-56-6
TH5427 is a lead NUDT5 inhibitor(MG assay IC50 = 29 nM).
  • $98
In Stock
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TH287
T20691609960-30-6
TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.
  • $31
In Stock
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TH5427 hydrochloride
T397852253744-57-7
TH5427 hydrochloride is a potent and selective inhibitor of NUDT5 with an IC50 of 29 nM. It demonstrates a remarkable 690-fold selectivity towards NUDT5 compared to MTH1. Moreover, TH5427 hydrochloride effectively inhibits progestin-dependent, PAR-derived nuclear ATP synthesis in breast cancer cells, thereby impeding chromatin remodeling, gene regulation, and ultimately suppressing proliferation.
  • $693
35 days
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