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Search Results for " nucleocapsid "

13

Compounds

Cat No. Product Name Synonyms Targets
T7353 RSV604 (S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea RSV
RSV604 ((S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea) is an inhibitor of respiratory syncytial virus (RSV) that binds to RSV nucleoprotein (Kd = 1.31 μM)
TP1814L CEF4 acetate CEF4 acetate(199727-68-9 free base) Others
CEF4 acetate (CEF4 acetate (199727-68-9 free base)) is a polypeptide corresponding to amino acid sequence 342-351 of the influenza A virus nucleocapsid protein.
T11409 GLP-26 HBV
GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM...
T35841 5-Benzyloxygramine Dopamine Receptor , 5-HT Receptor
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic inter...
T70246 PD159206
PD-159206 is a nucleocapsid inhibitor. It exhibits good antiviral activity against HIV.
TP1814 CEF4
CEF4 is a peptide derived from amino acids (aa) 342-351 of the influenza A virus nucleocapsid protein.
T24756 SAMT-247 SAMT 247
SAMT-247 is an HIV inhibitor that acts by modifying the nucleocapsid NCp7 region of Gag in infected cells and blocking Gag processing and reducing infectivity.
T61819 Claficapavir
Claficapavir (A1752) is a potent nucleocapsid protein (NC) inhibitor that effectively binds the HIV-1 NC with a dissociation constant (Kd) of 20 nM, resulting in the inhibition of its chaperone properties. This specific ...
T61613 SARS-CoV-2-IN-17
SARS-CoV-2-IN-17 (Compound 16) is a highly effective inhibitor of SARS-CoV-2 nucleocapsid protein (NPro). It demonstrates potent anti-viral activity, with an EC50 value of 2.18 μM. Furthermore, SARS-CoV-2-IN-17 binds to ...
T82230 HCoV-OC43-IN-1 SARS-CoV
HCoV-OC43-IN-1 (Compound IV-16) serves as an inhibitor of the coronavirus HCoV-OC43, exhibiting antiviral efficacy with an EC50 of 90 nM. It effectively inhibits the mRNA levels and expression of the viral nucleocapsid p...
T23407 Surface antigen (208-215) [Hepatitis B Virus] Others
The nucleocapsid of the hepatitis B virus is covered by an envelope of HBV surface antigen (HBsAg), which has the common, group-specific determinant a. The four major subtypes of HBsAg, adw, adr, ayw and ayr, are generat...
T60556 SARS-CoV-2-IN-16
SARS-CoV-2-IN-16 (Compound 12) is a potent inhibitor of SARS-CoV-2 nucleocapsid protein (NPro) with potent antiviral activity (EC50 = 3.69 μM). SARS-CoV-2-IN-16 binds to NPro with a low Kd value of 7.82 μM, which suggest...
T10446 BA-53038B Others
BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).
TargetMol