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ispinesib

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
Ispinesib
SB-715992, CK0238273
T2103336113-53-2
Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties.
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MC-Val-Cit-PAB-Ispinesib
T847031629737-40-1
MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].
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8-10 weeks
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AZD-4877
AZD4877
T9682758722-49-5In house
AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC).
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