indazole

Indazole is also called benzpyrazole or isoindazone. Its derivatives exhibit a wide range of biological activities. Indazole and its derivatives can be used in the research of cancer, neurological diseases, cardiovascular diseases, and gastrointestinal diseases.

Indazole-Cl is a selective ERß agonist and a selective estrogen receptor modifier (SERM).

Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells.

iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.

MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.

KP1019 is now discontinued.

1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid (Compound 31) is a metabolite of AB-FUBINACA. It acts as an MRGPRX4 antagonist with an IC50 greater than 2.5 μM.

4-Bromo-1H-indazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Indazole-3-carboxylic acid is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

6-Bromo-1H-indazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

5-Amino-1H-indazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

AB-CHMINACA 2'-indazole isomer has a structure similar to that of known synthetic cannabinoids.

3-Oxo-2,3-dihydro-1H-indazole-5-carboxylic acid is an intermediate used in the synthesis of various active compounds.

3-Methyl-6-nitro-1H-indazole is a pharmaceutical intermediate used in the synthesis of various active compounds.

2,3-Dimethyl-6-nitro-2H-indazole (Pazopanib Impurity) serves as a pharmaceutical intermediate used in the synthesis of various active compounds.

5-(1-Methylcyclopropoxy)-1H-indazole is a pharmaceutical intermediate used in the synthesis of various active compounds.

5-(Trifluoromethyl)-1H-indazole ,with CAS No. 885271-64-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-(Trifluoromethyl)-1H-indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Methyl-2H-indazole-3-carboxylic acid can be used as a potentially active molecular skeleton for the design and synthesis of biologically active compounds.

4-Fluoro-3-hydroxy (1H)indazole, with CAS No. 683748-50-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Fluoro-3-hydroxy (1H)indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-(Trifluoromethyl)-1H-indazole ,with CAS No. 1000339-98-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-(Trifluoromethyl)-1H-indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-Benzyl-3-hydroxy-1H-indazole ,with CAS No. 2215-63-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-Benzyl-3-hydroxy-1H-indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-Trifluoromethyl-5-aza-1H-indazole, with CAS No. 230305-81-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Trifluoromethyl-5-aza-1H-indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-fluoro-1H-Indazole-3-acetic acid,ethyl ester, with CAS No. 885271-93-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-fluoro-1H-Indazole-3-acetic acid,ethyl ester provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-Bromo-3-methyl-1H-indazole ,with CAS No. 552331-16-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Bromo-3-methyl-1H-indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.