indazole

Indazole is also called benzpyrazole or isoindazone. Its derivatives exhibit a wide range of biological activities. Indazole and its derivatives can be used in the research of cancer, neurological diseases, cardiovascular diseases, and gastrointestinal diseases.

Indazole-Cl is a selective ERß agonist and a selective estrogen receptor modifier (SERM).

2-Methyl-2H-indazole-3-carboxylic acid can be used as a potentially active molecular skeleton for the design and synthesis of biologically active compounds.

4-Fluoro-3-hydroxy (1H)indazole, with CAS No. 683748-50-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Fluoro-3-hydroxy (1H)indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-Trifluoromethyl-5-aza-1H-indazole, with CAS No. 230305-81-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Trifluoromethyl-5-aza-1H-indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-fluoro-1H-Indazole-3-acetic acid,ethyl ester, with CAS No. 885271-93-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-fluoro-1H-Indazole-3-acetic acid,ethyl ester provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid (Compound 31) is a metabolite of AB-FUBINACA. It acts as an MRGPRX4 antagonist with an IC50 greater than 2.5 μM.

4-Bromo-1H-indazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Indazole-3-carboxylic acid is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

6-Bromo-1H-indazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

5-Amino-1H-indazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

AB-CHMINACA 2'-indazole isomer has a structure similar to that of known synthetic cannabinoids.

3-Bromo-7-nitroindazole is a specific neuronal nitric oxide synthase (nNOS) inhibitor that affects the synthesis of the intercellular messenger NO throughout the brain and body.

7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.

1-Methylindazole-3-carboxylic acid is an excellent solvent with a proper boiling point.

5-Fluoro-3-indazolecarboxylic acid, with CAS No. 1077-96-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Fluoro-3-indazolecarboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-Hydroxyindazole is a useful organic compound for research related to life sciences. The catalog number is T67133 and the CAS number is 23244-88-4.

Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2 M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells.

2H-Pyrido[2',1':3,4]pyrazino[1,2-b]indazole-3-carboxylic acid, 6-(1, 1-Dimethylethyl)-6, 7-Dihydro-10 -(3-methoxypropoxy)-2-oxo-, (6R)- has antibacterial and antiviral activity and can be used to study Hepatitis B virus.

Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).

iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.

Glucagon receptor antagonists-5 is an orally bioavailable indazole-based glucagon receptor antagonist (Ki: 32 nM). It has potential for the treatment of type 2 diabetes mellitus (T2DM).

FKK [N-(heptyloxycarbonylaminosulfonyl)-2-aminobenzamide] is an indazole derivative and a novel bronchodilator.

AB-FUBINACA 3-fluorobenzyl isomer is a synthetic cannabinoid and an indazole derivative, exhibiting high affinity for central CB1 receptors (Ki= 0.9 nM) and possessing anticonvulsant activity.