hk2

UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability.

SphK2-IN-2 (21g) is a potent and selective SphK2 inhibitor with an IC50 of 0.23 μM.

SphK2-IN-1 is an SphK2 inhibitor with an IC50 value of 0.359 μM. SphK2-IN-1 can be used to study cancer, inflammation, neurological and cardiovascular diseases.

Chk2-IN-2 (compound 2) serves as a selective CHK2 inhibitor, showing promise for anticancer applications [1].

CUHK242 is a bacterial transcription inhibitor that exhibits antimicrobial activity against Staphylococcus aureus (Staphylococcus aureus). It inhibits RNA synthesis within cells, consequently reducing protein synthesis. For the Bacillus subtilis strain BS2019 (B. subtilis), the minimum inhibitory concentration (MIC) of CUHK242 is reported to be 2 μg/mL.

L-Ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.

Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.

Tuvatexib is a small molecule VDAC/HK2 dual modulator.

SH514 is a specific IRF4 inhibitor with an IC₅₀ of 2.63 µM, binding to the DNA-binding domain (IRF4-DBD) of IRF4 to block its transcriptional activity and inhibit the expression of downstream genes such as CCNC, CANX, E2F5, CMYC, HK2, and Blimp1, and inhibits the expression of MM cell cycle-related proteins CDC2, Cyclin B1, Cyclin D1, Cyclin E1, and CMYC, making it useful for studying multiple myeloma and malignant haematological diseases.

Benitrobenrazide (Hexokinase 2 inhibitor 1) is a hexokinase 2 inhibitor with anticancer and antitumor activity.Benitrobenrazide inhibits the growth of tumors and can be used in cancer research.

Pro-Phe-Arg-AMC acetate is a peptide that serves as a substrate for human glandular kallikrein 2 (hK2).