flavonol

Flavonol (3-Hydroxyflavone) is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, pomegranate, red raspberry, and fenugreek. 3-hydroxyflavone is a chemical compound. It is the backbone of all flavonols, a type of flavonoid. It serves as a model molecule as it possesses an excited-state intramolecular proton transfer (ESIPT) effect to serve as a fluorescent probe to study membranes for example or intermembrane proteins.

Azaleatin is a natural product from Rhododendron simsii. Azaleatin is a dipeptidyl peptidase-IV inhibitor. Azaleatin can be used for type-2 diabetes and obesity studies.

Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside (Quercetin 3-O-(6''-galloyl)-beta-D-glucopyranoside) is a natural product with potent inhibitory activity against the growth of Microcystis aeruginosa.

Glycyrrhiza flavonol A is a natural product of Glycyrrhiza, Fabaceae. The catalog number is TN4150 and the CAS number is 197304-01-1. Glycyrrhiza flavonol A can be used as a reference standard.

4'-Methoxyflavonol is a synthetic flavonol with an additional 3-hydroxyl group and higher antioxidant capacity than 4'-Methoxyflavone.4'-Methoxyflavonol interacts with the lipid bilayer of DPPC model membranes, and is capable of scavenging free radicals and antioxidant activity in DPPH assays, and exhibits some antiproliferative activity against K562 and MCF-7 cancer cell lines.

Broussoflavonol B is a useful organic compound for research related to life sciences and the catalog number is T123814.

7-Hydroxy-6-methoxydihydroflavonol is a useful organic compound for research related to life sciences. The catalog number is T125011 and the CAS number is 34050-66-3.

3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant that reduces ROS and superoxide production in the mesenteric arteries of diabetic rats, increases total eNOS expression, and improves nitric oxide (NO) activity.

3'-Methoxyflavonol is a potent, selective agonist of neuromedin U 2 receptor (NMU2R).

Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggregation. Broussoflavonol F shows inhibitory activities on mushroom tyrosinase. Broussoflavonol F

6-Hydroxykaempferol 3-beta-rutinoside is a natural product

Isolicoflavonol is a potential cancer chemopreventive agent.

Licoflavonol is a flavonoid compound that can be extracted from licorice. It is an inhibitor of Salmonella Typhimurium serotype 3 secretion system and suppresses the secretion of Abeta by inhibiting β-site APP cleaving enzyme 1 (BACE1) transcription.

4'-hydroxy-6,7,8,3'-tetramethoxyflavonol is a natural product for research related to life sciences. The catalog number is TN3038 and the CAS number is 1879030-01-9.

7-Methoxyflavonol is a natural flavonoid exhibiting inhibitory activity against NCI-H460, MCF-7, and A375-C5 cells, along with anti-Trypanosoma and anti-Leishmania activities.

Dodonaflavonol is a natural product for research related to life sciences. The catalog number is TN3880 and the CAS number is 1392213-93-2.

Broussoflavonol G is an active component found in plants of the Moraceae family, which can be isolated from Broussonetia papyrifera. It effectively inhibits Fe(2+)-induced lipid peroxidation in rat brain homogenate and significantly suppresses the proliferation of rat vascular smooth muscle cells.

1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.

Isoastilbin is a dihydroflavonol glycoside compound found in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL and possesses anti-acne and tyrosinase inhibition properties. Additionally, isoastilbin demonstrates neuroprotective, antioxidation, antimicrobial, and anti-apoptotic properties, indicating potential for Alzheimer's disease research.

7-Prenyloxyaromadendrin is a natural product for research related to life sciences. The catalog number is TN5535 and the CAS number is 78876-50-3.

Icariin (Ieariline) belongs to the flavonol glycoside group of natural products, can inhibit PDE5 and PDE4 activity (IC50=432/73.50 μM), is also a PPARα activator. Icariin can increase cardiovascular and cerebrovascular blood flow, promote hematopoiesis, immunity and bone metabolism.

Leucoside (Kaempferol 3-sambubioside) is a naturally occuring flavonol bioside with many biological activities.

Sinocrassoside C1 is the methanolic extract of the whole plant of Sinocrassula indica (Crassulaceae), six new flavonol glycosides

Tubulin polymerization-IN-83 (Compound A23) is a flavonol derivative with antifungal activity against various plant pathogenic fungi. It has an EC50 of 0.338 μg/mL against Botrytis cinerea. The compound works by targeting β-tubulin, disrupting hyphal morphology, and affecting cell membrane permeability, while posing low ecological risk.