da-6

Diethyl aminoethyl hexanoate citrate (2-Diethylaminoethyl hexanoate citrate) is a compound that is widely used as a plant growth regulator stimulates the regeneration of adventitious buds.

RGD-DA6 is an αvβ3-targeting ligand composed of RGDfK (an RGD peptide targeting integrin αvβ3), DOTADG, d-Glu, Lys, AMBA, and IPBA. Through radiolabeling, RGD-DA6 forms an αvβ3-targeted radioligand for high-contrast tumor imaging and improved anticancer efficacy.

DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.

Takeda-6d, a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor, inhibits B-RAF and VEGFR2 with IC50 of 7.0nM and 2.2nM.

Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug.

2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).

Lipid A6 is a biodegradable alkyne lipid used in the synthesis of lipid-like nanoparticles (LNPs) for mRNA delivery.

Recflavone( DA-6034) is a synthetic derivative of eupatilin and flavonoids that have anti-inflammatory effects against inflammatory bowel disease.

AL-GDa62, a potential synthetic lethal agent for gastric cancer treatment, demonstrates efficacy with EC50 values of 3.2 μM in MCF10A-WT (wild-type) isogenic mammary epithelial cells and 2 μM in MCF10A-CDH1 -/- cells [1].

Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent acute liver injury.

Centanafadine is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).

Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).

C-DIM12 induced expression of Nurr1-regulated genes. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and enhanced neuronal survival from exposure to 6-OHDA.

N6-Methyl-dA phosphoramidite is utilized in the synthesis of oligodeoxyribonucleotides [sodium (5'-deoxyadenosyl nucleotide)] by incorporating methyl groups at the N6 position.

5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.

5'-O-DMT-N6-Me-2'-dA is a nucleoside that exhibits protective and modification effects.

Dasotraline is a triple reuptake inhibitor that blocks dopamine (DA), norepinephrine (NE), and serotonin [5-hydroxytryptamine (5-HT)] transporters with IC50 values of 4, 6, and 11 nM, respectively, representing a potential new class of antidepressant agents.

6-Arm-PEG-DA (MW 10000) is a polymer consisting of a six-armed PEG core where acrylate groups are chemically linked to the end of each PEG chain, making it suitable for drug delivery applications.

6-Arm-PEG-DA (MW 3400) is a polymer featuring a four-arm PEG core structure, where acrylate groups are chemically attached to the end of each PEG chain. It is utilized in drug delivery applications.

6-Arm-PEG-DA (MW 400) is a polymer consisting of a six-arm polyethylene glycol (PEG) core, with acrylate groups chemically bonded to the end of each PEG chain, and is applicable in drug delivery systems.

6-Arm-PEG-DA (MW 5000) is a polymer featuring a six-arm polyethylene glycol (PEG) core, with acrylate groups chemically bonded to the end of each PEG chain, making it suitable for drug delivery applications.

6-Arm-PEG-DA (MW 1000) is a polymer with a six-arm PEG core, where acrylate groups are chemically bonded to the end of each PEG chain. This compound is suitable for drug delivery applications.

6-Arm-PEG-DA (MW 600) is a polymer composed of a six-arm PEG core, with acrylate groups chemically linked to the end of each PEG chain, and is applicable in drug delivery.

6-Arm-PEG-DA (MW 2000) is a polymer featuring a six-arm PEG core structure, where acrylate groups are chemically bonded to the end of each PEG chain. This compound is applicable in drug delivery.