cardioselective

Atenolol (Tenormin) is a selective β1 receptor antagonist.

Timolol is a nonselective beta-adrenergic receptor blocker that is widely used for the therapy of hypertension, angina pectoris and prevention of vascular headaches.

Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity. It is used in the management of ANGINA PECTORIS and HYPERTENSION.

(±)-Prenalterol (H 80/62) is a new cardioselective positive inotropic compound that is an agonist of beta-2- and beta-1-adrenergic receptors and can be used to study chronic congestive heart failure.

Ridazolol is a vasodilating and cardioselective beta adrenergic blocker.

Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is used to manage HYPERTENSION and chronic HEART FAILURE in elderly patients.

Betaxolol hydrochloride (SL 75212 HCl) is a cardioselective beta-blocker used in the treatment of hypertension.Betaxolol hydrochloride has not been linked to instances of clinically apparent drug induced liver injury.

Labetalol hydrochloride (Sch-15719W), a salicylamide derivative, is a non-cardioselective blocker of β-adrenergic receptors and α1-adrenergic receptors.

Acebutolol hydrochloride (Acebutolol HCl) acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Acebutolol hydrochloride is the hydrochloride salt form of acebutolol, a synthetic butyranilide derivative with hypotensive and antiarrhythmic activity. Having stabilizing and quinidine-like effects on cardiac rhythm, Acebutolol hydrochloride is used in ventricular arrhythmias. Other indications include hypertension, alone or in combinations with other agents.

(R)-(+)-Atenolol ((R)-Atenolol) is a cardioselective beta-1 adrenergic blocker, which properties are similar to propranolol, but without a negative inotropic effect.

Metoprolol Tartrate is a blocker of the cardioselective β-adrenergic receptor.

Ko-3290 is a cardioselective antagonist of β-adrenoceptors known for its antilipolytic effects in animals.

U-89232 is an opener of the cardioselective KATP channel.

Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension. Esmolol has not been linked to instances of clinically apparent drug induced liver injury.

Levobetaxolol, also known as AL-1577A and Betaxon, is a cardioselective β-adrenergic receptor inhibitor. It has been demonstrated to reduce intraocular pressure in patients affected by ocular hypertension and primary open-angle glaucoma.

Esmolol is an ultra-short-acting, cardioselective β1-adrenergic receptor blocker. Esmolol exerts antiarrhythmic effects by regulating the NK1 receptor (neurokinin 1 receptor) signaling pathway and effectively improves myocardial dysfunction after cardiopulmonary resuscitation.Esmolol can positively promote diabetic wound healing by inhibiting aldose reductase activity, reducing advanced glycation end-product formation, and promoting fibroblast migration.Esmolol serves as an important tool drug for mechanistic studies on cardiovascular diseases such as arrhythmias and diabetic foot ulcers.

Acebutolol is a cardioselective beta-1 adrenergic antagonist with antiarrhythmic and hypotensive activity and little effect on the bronchial receptors. Acebutolol has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympa

Nebivolol, a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect, is used in treatment of hypertension, in Europe, it is also used for left ventricular failure. It is highly cardioselective under certain circumstances.

Bisoprolol is a cardioselective β1-adrenergic blocker used for secondary prevention of heart failure, myocardial, angina pectorisinfarction (MI) and mild to moderate hypertension.

Dilevalol ((+)-Labetalol) is a selective β2-adrenergic receptor agonist and non-selective β-adrenergic receptor blocker used to treat hypertension and angina pectoris.

DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delayed rectifier potassium currents.

LY 249933 is a cardioselective 1, 4-dihydropyridine with positive inotropic activity.

Methoctramine tetrahydrochloride is a potent and cardioselective antagonist of the M2 muscarinic receptor, capable of inhibiting muscarine-induced bradycardia in vivo.

Landiolol is used as a highly cardioselective ultra short-acting beta-blocker.