bpp

BPP is a fluorescent microviscosity probe used to image natural HOBr in living cells and zebrafish.

BPP-2 is a GHSR ligand containing the element F. By labeling BPP-2 with the isotope 18F, a PET probe targeting GHSR can be produced. The binding affinity (Ki) of 18F-BPP-2 for GHSR is 274 nM.

HMBPP triammonium is a stimulator of gamma delta T cells.

HMBPP analog 1 (6e), a trifluoromethyl analog, acts as a potent inhibitor and a weak agonist in the HMBPP ELISA assay.

HMBPP lithium is an intermediate in isoprene biosynthesis, produced by bacteria and protozoa using the non-mevalonate pathway. It serves as a ligand for the inner domain of BTN3A1 and acts as an activator of human Vγ9/Vδ2T cells. Additionally, HMBPP lithium stimulates feeding behavior in mosquitoes.

Prolyl Endopeptidase Inhibitor 1 is a potent inhibitor of prolyl endopeptidase (PEP; PE)(Ki : 15 nM) , has anti-amnesic effect.

Compound BPP (HDGFRP2/PSIP1-IN-1) is a dual inhibitor targeting the PWWP domains of Hepatoma-derived Growth Factor Related Protein 2 (HDGFRP2) and its homologue PSIP1. This compound effectively hinders the occurrence and progression of Diffuse Intrinsic Pontine Glioma (DIPG). It demonstrates binding affinity with a Kd value of 7 μM for HDGFRP2, indicative of its efficient ligand efficacy at 0.47. Additionally, Compound BPP exhibits a Kd value of 27 μM when binding to the PSIP1 PWWP domain, and a Kd value of 14 μM against HDGFRP3, confirming its potency as an inhibitor within the HDGFRP2 PWWP subfamily.

Bradykinin potentiator-5 is a peptide inflammatory mediator, causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall.

KH064 is a sPLA2-IIA inhibitor of oral activity.