toxoplasma — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN7103	13,21-Dihydroeurycomanone	Pasakbumin C	Anti-infection , Parasite
	13,21-Dihydroeurycomanone (Pasakbumin C) is a natural product isolated from the root of Eurycoma longifolia with antiparasitic activity such as Plasmodium falciparum and Toxoplasma gondii.		Anti-infection , Parasite
T1172	Diclazuril	R-64433	Antibiotic , Parasite
	Diclazuril (R-64433) is a coccidiostat.		Antibiotic , Parasite
T25549	JCP174	JCP 174,JCP-174	Serine Protease
	JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1.		Serine Protease
T78605	CpCDPK1/TgCDPK1-IN-1		Bcr-Abl , Src
	CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections and cryptosporidiosis.		Bcr-Abl , Src
T36692	Fanotaprim		DHFR
	Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor. Fanotaprim inhibits the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM and a hDHFR IC50 of 308 ± 71 nM and a hDHFR to TgDHFR selectivity ratio o...		DHFR
T72081	CpCDPK1/TgCDPK1-IN-2		Parasite
	CpCDPK1/TgCDPK1-IN-2 is a dual inhibitor of CpCDPK1 and TgCDPK1 with IC50 values of 12 and 5 nM for CpCDPK1 and TgCDPK1, respectively.CpCDPK1/TgCDPK1-IN-2 can be used in the study of diseases associated with infection of...		Parasite
T0819	Spiramycin	Espiramicin,Sequamycin,Rovamycin,Provamycin,Formacidine	Antibacterial , Antibiotic , Parasite
	Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens. The drug is effective against gram-positive aerobic pathogens, N. gonorrhoeae, and staphylococci. It is used to treat infections caus...		Antibacterial , Antibiotic , Parasite
T72033	PCDPK1/TgCDPK1-IN-3		Parasite
	CpCDPK1/TgCDPK1-IN-3 is a dual inhibitor of CpCDPK1 and TgCDPK1 with an IC50 of 0.003 µM for CpCDPK1 and 0.0036 µM for TgCDPK1. CpCDPK1/TgCDPK1-IN-3 can be used to study infections associated with diseases such as Toxopl...		Parasite
T62333	Anti-Trypanosoma cruzi agent-1
	Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.
T29003	TRC-19
	TRC-19 is a potent and selective inhibitor of Toxoplasma gondii dihydrofolate reductase. TRC-19 shows an IC50 of 9 nM and 89-fold selectivity in favor of Toxoplasma gondii dihydrofolate reductase.
T61671	MMV687807
	MMV687807 is a potent anthelmintic compound exhibiting strong efficacy against Toxoplasma gondii (T. gondii). It demonstrates an IC50 value of 0.15 μM and a CC50 value of 1.69 μM [1].
T69311	GW300657X
	GW300657X is a small molecule inhibitor that blocks toxoplasma gondii rhoptry kinase 18 and maintains moderate CDK2-cyclin A inhibitory activity.
T76121	Phosphoglucomutase		Endogenous Metabolite
	Phosphoglucomutase promotes cyst development in Toxoplasma gondii. Deficiency of Phosphoglucomutase causes metabolic disorders.		Endogenous Metabolite
T38269	Purfalcamine
	Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes mala...
T35750	Trypacidin
	Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, re...