Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Antifolate
    (27)
  • DHFR
    (14)
  • DNA/RNA Synthesis
    (8)
  • Apoptosis
    (5)
  • Parasite
    (4)
  • Antibacterial
    (3)
  • Autophagy
    (3)
  • Dehydrogenase
    (3)
  • ADC Cytotoxin
    (2)
  • Others
    (20)
Filter
Search Result
Results for "

Antifolate

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    51
    TargetMol | Inhibitors_Agonists
  • Inhibitory Antibodies
    6
    TargetMol | Inhibitory_Antibodies
  • Dye Reagents
    1
    TargetMol | Dye_Reagents
  • PROTAC Products
    1
    TargetMol | PROTAC
  • Natural Products
    5
    TargetMol | Natural_Products
  • Recombinant Protein
    1
    TargetMol | Recombinant_Protein
Trimethoprim
NSC-106568, NIH 204, BW 56-72
T1153738-70-5
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.
  • Inquiry Price
Size
QTY
Methotrexate
WR19039, NCI-C04671, CL14377, Amethopterin
T148559-05-2
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and various tumors.
  • Inquiry Price
Size
QTY
Calcium N5-methyltetrahydrofolate
NSC173328
T759826560-38-3
Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers
  • Inquiry Price
Size
QTY
Farletuzumab
MORAb-003
T76720896723-44-7
Farletuzumab (MORAb-003) is a humanized monoclonal antibody with a high affinity for folate receptor-α (FRα), acting as a potent inhibitor of FRα and impeding the growth of cells that overexpress this receptor, making it useful for cancer research.
  • Inquiry Price
Size
QTY
Mirvetuximab
M9346A
T767661453084-36-0
Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form antibody-drug conjugates for the treatment of ovarian cancer and other FRα-positive cancers.
  • Inquiry Price
Size
QTY
DHFR-IN-3
7-bromoquinazoline-2,4-diamine
T3693137553-43-6
DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is a dihydrofolate reductase (DHFR) inhibitor.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
Antifolate C2
AGF-154, AGF154, AGF 154
T266361286279-90-0In house
Antifolate C2 (AGF 154) has antitumor activity with an IC of 0.14 nM measured in a growth inhibition assay of human tumor cells.Antifolate C2 can be used for the study of cancer and autoimmune diseases.
  • Inquiry Price
6-8 weeks
Size
QTY
Antifolate C1
AGF 94,AGF94,AGF-94
T26635136784-51-5
Antifolate C1 is an inhibitor of de novo purine biosynthesis. Antifolate C1 has selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter (PCFT) over the reduced folate carrier (RFC).
  • Inquiry Price
8-10 weeks
Size
QTY
Mirvetuximab soravtansine
TAK-853, IMGN-853, IMGN853
T778251453084-37-1
Mirvetuximab soravtansine (IMGN853) is an antibody-drug coupling (ADC) targeting folate receptor alpha (FRα), which inhibits cell growth and enhances the antiproliferative effects of DNA damage, and may be useful in the study of drug-resistant ovarian cancer.
  • Inquiry Price
7-10 days
Size
QTY
Mirvetuximab-DM4
M9346A-DM4
T9901A-480
Mirvetuximab-DM4 (M9346A-DM4) is a compound targeting FOLR1 with potential anti-cancer activity. It can be used to synthesize Mirvetuximab soravtansine and study ovarian cancer.
    Inquiry
    Methotrexate metabolite
    DAMPA
    T1604519741-14-1In house
    Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant.
    • Inquiry Price
    Size
    QTY
    Folinic acid calcium
    Wellcovorin, Leucovorin Calcium, Folinic acid calcium salt, Calcium folinate
    T01481492-18-8
    Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.
    • Inquiry Price
    Size
    QTY
    Folinic Acid Calcium Salt Pentahydrate
    Leucovorin calcium salt pentahydrate, Leucovorin Calcium Pentahydrate
    T0148L6035-45-6
    Folinic Acid Calcium Salt Pentahydrate (Leucovorin Calcium Pentahydrate), a reduced folic acid, is used in combination with other chemotherapeutics.
    • Inquiry Price
    Size
    QTY
    Pemetrexed
    Pemetrexed acid, LY231514 Disodium Hydrate, LY231514
    T0189137281-23-3
    Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).
    • Inquiry Price
    Size
    QTY
    Pemetrexed disodium
    LY231514 disodium
    T0189L150399-23-8
    Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has been associated with moderate rates of serum enzyme elevations during therapy, but has not been convincingly linked to instances of acute, clinically apparent liver injury.
    • Inquiry Price
    Size
    QTY
    Pyrimethamine
    RP 4753, Pirimetamin, Pirimecidan
    T084958-14-0
    Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.
    • Inquiry Price
    Size
    QTY
    Diaveridine
    EGIS-5645, CCRIS-3784, AI3-23935
    T22045355-16-8
    Diaveridine (AI3-23935) (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to mammalian cells, but more studies are required to clarify this.
    • Inquiry Price
    Size
    QTY
    Folinic acid
    Leucovorin, HSDB 6544
    T2440358-05-9
    Folinic acid (Leucovorin) is a biofolate used in the treatment of methotrexate (MTX) toxicity reduction and as an adjuvant therapy for colon cancer.
    • Inquiry Price
    7-10 days
    Size
    QTY
    Levoleucovorin Calcium
    CL307782, Calcium Levofolinate
    T643180433-71-2
    Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.
    • Inquiry Price
    Size
    QTY
    Levomefolate calcium
    T7593151533-22-1
    Levomefolate calcium, an artificial form of folate, is a coenzymated form of folic acid that offers a more bioavailable alternative in dietary supplements.
    • Inquiry Price
    Size
    QTY
    Methotrexate disodium
    T80037413-34-5
    Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
    • Inquiry Price
    Size
    QTY
    Pemetrexed disodium hemipenta hydrate
    Pemetrexed Disodium Hydrate, LY-231514 Disodium Hydrate, Pemetrexed sodium hydrate
    T6226357166-30-4
    Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 65 nM, respectively.
    • Inquiry Price
    Size
    QTY
    Metoprine
    T85487761-45-7
    Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.
    • Inquiry Price
    Size
    QTY
    Trimethoprim lactate
    BW56-72 lactate, NIH204 lactate, NSC-106568 lactate, NIH 204 lactate, Primsol lactate, BW 56-72 lactate
    T3986223256-42-0
    Trimethoprim lactate (NSC-106568 lactate) is an antibiotic that inhibits bacterial dihydrofolate reductase (DHFR). Trimethoprim lactate has demonstrated antimicrobial activity, with excellent inhibition of Gramnegative bacteria. Trimethoprim lactate is used alone for the Trimethoprim lactate is used alone or in combination with other antibiotics to treat a variety of eye, lung, and gastrointestinal infections.
    • Inquiry Price
    7-10 days
    Size
    QTY