2 NP

2-NP is a STAT1 enhancer.

2-NP-AMOZ is a 2-nitrophenyl derivative of AMOZ, a metabolite of the antibiotic Furaltadone, serving as a reliable tool for protein-bound AMOZ detection.

2-NP-AOZ is a chemical compound that is a 2-nitrophenyl derivative of AOZ, which is a tissue-bound metabolite of Furazolidone. 2-NP-AOZ is specifically used for the determination of AOZ residues.

2-NP-AHD, a 2-nitrophenyl derivative of AHD, is a metabolite of nitrofurans, a class of antibiotics, and serves as an indicator for the detection of illicit use of nitrofuran drugs.

2-NP-AOZ-d4 is a deuterated compound of 2-NP-AOZ. 2-NP-AOZ has a CAS number of 19687-73-1. 2-NP-AOZ is a chemical compound that is a 2-nitrophenyl derivative of AOZ, which is a tissue-bound metabolite of Furazolidone. 2-NP-AOZ is specifically used for the determination of AOZ residues.

2-NP-AMOZ-d5 is a deuterated compound of 2-NP-AMOZ. 2-NP-AMOZ has a CAS number of 183193-59-1. 2-NP-AMOZ is a 2-nitrophenyl derivative of AMOZ, which is a metabolite of the antibiotic Furaltadone. This chemical compound specifically serves as a reliable tool for protein bound AMOZ detection.

2-NP-AHD (Standard) is the standard substance of 2-NP-AHD, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 2-NP-AHD is a 2-nitrophenyl derivative of AHD, which is a metabolite of nitrofurans, a class of antibiotics. It serves as an indicator for the detection of illicit use of nitrofuran drugs.

2-NP-AMOZ (Standard) is the standard substance of 2-NP-AMOZ, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 2-NP-AMOZ is a 2-nitrophenyl derivative of AMOZ, which is a metabolite of the antibiotic Furaltadone. This chemical compound specifically serves as a reliable tool for protein bound AMOZ detection.

2-NP-AOZ (Standard) is the standard substance of 2-NP-AOZ, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 2-NP-AOZ is a chemical compound that is a 2-nitrophenyl derivative of AOZ, which is a tissue-bound metabolite of Furazolidone. 2-NP-AOZ is specifically used for the determination of AOZ residues.

Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autophagy.

Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.

Cyclosporin A is a natural product and an active fungal metabolite, classified as a cyclic polypeptide immunosuppressant. It binds to cyclophilin and inhibits the activity of calcineurin (IC₅₀ = 7 nM) as well as CD11a/CD18 adhesion molecules. It is commonly used to induce uremia models.

Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis.

Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner. Erastin has anti-tumor activity and acts selectively on tumor cells with RAS-carcinogenic mutations.

Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.

(-)-Epigallocatechin Gallate (EGCG) is a phenolic antioxidant polyphenol flavonoid found in plants such as green and black tea, which inhibits telomerase and DNA methyltransferase, blocks the activation of EGF receptors and HER-2 receptors, inhibits cellular oxidation, and prevents free radical damage to cells.

Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces apoptosis.

BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.BI-2493 exhibits antitumor activity and inhibits tumor cell growth and can be used in the study of cancerous diseases.BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.

RMC-6236 is an orally effective and novel triple complex RAS (ON) MULTI inhibitor, which is a potent non covalent inhibitor of multiple RAS variants in GTP binding state. RMC-6236 has anti-tumor activity and can be used in research related to RAS driven tumors. With rich experience in compound synthesis, we can provide fast customized synthesis services for this product according to your research needs.

MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.

Pioglitazone (U 72107) is a PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively, and has selective and oral activity. Pioglitazone can be used in diabetes research.

Cyclophosphamide is an alkylating agent type of anti-tumor drug, and its main target is DNA. Cyclophosphamide inhibits the proliferation of tumor cells by undergoing alkylation reactions with DNA, interfering with the replication and transcription processes of DNA.

Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride), a widely used anti-diabetic drug, exhibits potential anti-Y properties by inhibiting the proliferation of various Y cells, including colon and prostate.

Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.