2'-deoxyguanosine

2'-Deoxyguanosine (Guanine deoxyriboside) is a purine nucleoside that is recognized by members of the 2'-dG-II family.2'-Deoxyguanosine has been associated with aging, mutation, and carcinogenesis, and is oxidized by molecular oxygen.

2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.

Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate), a sulfur-containing isomer of 2'-deoxyguanosine-5'-O-triphosphate (dGTP), functions as an inhibitor of the deoxynucleoside triphosphate triphosphohydrolase SAMHD1, with an inhibitory constant (Ki) of 820 nM.

6-O-Propynyl-2'-deoxyguanosine, a click chemistry reagent with an alkyne group, facilitates research in various biochemical [1] contexts.

2'-Deoxyguanosine-D13 is a deuterium-labeled form of 2'-Deoxyguanosine (T22218) (Deoxyguanosine), also known as guanine deoxyriboside.

8-Hydroxy-2'-deoxyguanosine-15N5 is the 15N labeled version of 8-Hydroxy-2'-deoxyguanosine (TMSM-3709). This compound serves as a crucial biomarker for oxidative stress and carcinogenesis.

8-Bromo-2'-deoxyguanosine is a 2'-deoxynucleoside and a halo-nucleoside.

8-Benzyloxy-2'-deoxyguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.

8-Methyl-2'-deoxyguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.

2'-Amino-2'-deoxyguanosine is a nucleoside antibiotic that exhibits lethal activity against certain strains of Escherichia coli. Its antibacterial effects can be reversed by guanosine and other purine nucleosides. This compound can be utilized in the study of bacterial infections.

Nucleoside Derivatives - 7-Deaza-purine nucleoside

Nucleoside Derivatives –2'-Deoxy nucleoside; 2-Modified nucleoside; Drugs and Inhibitors; DNA adduct MF-dG

Nucleoside Derivatives –8-Modified purine nucleosides

Nucleoside Derivatives –8-Modified purine nucleosides; Alpha-nucleosides

7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 of 11 μM [1].

8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases.

2'-Deoxyguanosine 5'-monophosphate disodium (5'-dGMP disodium) is a GTP derivative that serves as an oxidizable target and is used in forming polycomplexes with other compounds.

2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA. 2'-Deoxyguanosine monohydrate can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion.

7-Iodo-7-deaza-2'-deoxyguanosine is a deoxyguanosine derivative used in DNA synthesis and sequencing reactions.

6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.

2'-Deoxyguanosine-13C10 is a version of 2'-Deoxyguanosine (T22218) that has been labeled with 13C. The compound '2'-Deoxyguanosine, also known simply as Deoxyguanosine, is a deoxyribonucleoside of guanine.

2'-Deoxyguanosine-13C10,15N5 is a variant of 2'-Deoxyguanosine (T22218) that has been isotopically labeled with carbon-13 and nitrogen-15.

8-Hydroxy-2'-deoxyguanosine (Standard) is a reference standard for research and analysis in studies involving 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases.

2'-Deoxyguanosine-[1',2',3',4',5'-13C5] Monohydrate (Standard) is a reference standard of 2'-Deoxyguanosine-[1',2',3',4',5'-13C5] Monohydrate intended for quantitative analysis, quality control, and related biochemical research applications.