2'-deoxyguanosine

2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.

Nucleoside Derivatives - 7-Deaza-purine nucleoside

Nucleoside Derivatives –2'-Deoxy nucleoside; 2-Modified nucleoside; Drugs and Inhibitors; DNA adduct MF-dG

Nucleoside Derivatives –8-Modified purine nucleosides; Alpha-nucleosides

2'-Deoxyguanosine (Guanine deoxyriboside) is a purine nucleoside that is recognized by members of the 2'-dG-II family.2'-Deoxyguanosine has been associated with aging, mutation, and carcinogenesis, and is oxidized by molecular oxygen.

Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate), a sulfur-containing isomer of 2'-deoxyguanosine-5'-O-triphosphate (dGTP), functions as an inhibitor of the deoxynucleoside triphosphate triphosphohydrolase SAMHD1, with an inhibitory constant (Ki) of 820 nM.

6-O-Propynyl-2'-deoxyguanosine, a click chemistry reagent with an alkyne group, facilitates research in various biochemical [1] contexts.

2'-Deoxyguanosine-d13 (Deoxyguanosine-d13; Guanine deoxyriboside-d13) is a deuterium-labeled form of 2'-Deoxyguanosine (Deoxyguanosine), also known as guanine deoxyriboside.

8-Hydroxy-2'-deoxyguanosine-15N5 is the 15N labeled version of 8-Hydroxy-2'-deoxyguanosine. This compound serves as a crucial biomarker for oxidative stress and carcinogenesis.

8-Bromo-2'-deoxyguanosine is a 2'-deoxynucleoside and a halo-nucleoside.

8-Benzyloxy-2'-deoxyguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.

8-Methyl-2'-deoxyguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.

Nucleoside Derivatives –8-Modified purine nucleosides

7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 of 11 μM [1].

8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases.

2'-Deoxyguanosine 5'-monophosphate disodium (5'-dGMP disodium) is a GTP derivative that serves as an oxidizable target and is used in forming polycomplexes with other compounds.

2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA. 2'-Deoxyguanosine monohydrate can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion.

7-Iodo-7-deaza-2'-deoxyguanosine is a deoxyguanosine derivative used in DNA synthesis and sequencing reactions.

6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.

2'-Deoxyguanosine-13C10 (Deoxyguanosine-13C10; Guanine deoxyriboside-13C10) is a version of 2'-Deoxyguanosine that has been labeled with 13C. The compound '2'-Deoxyguanosine, also known simply as Deoxyguanosine, is a deoxyribonucleoside of guanine.

2'-Deoxyguanosine-13C10,15N5 (Deoxyguanosine-13C10,15N5; Guanine deoxyriboside-13C10,15N5) is a variant of 2'-Deoxyguanosine that has been isotopically labeled with carbon-13 and nitrogen-15.

8-Hydroxy-2'-deoxyguanosine (Standard) is a reference standard for research and analysis in studies involving 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases.

N2-Isobutyryl-2-deoxyguanosine（iBu-dG） is a nucleoside analog that can be used to synthesize oligonucleotides.

Nucleoside Derivatives - 7-Deaza-purine nucleoside; 2'-Deoxy Toyocamycin