Plantaginaceae

Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).

Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis.

Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitro with the IC(50) value of 2.17 mM, it also shows inhibitory activity against PKCalpha with the IC50 value14.8microM.

1. Pectolinarigenin (Pectolinaringenin) exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that they may inhibit eicosanoid formation in inflammatory lesions.

Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.

Plantamajoside (Y0160) has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity.

Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias associated with reentry mechanisms. It inhibits the Na-K-ATPase membrane pump, increasing intracellular sodium and calcium concentrations.

Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of α2-amyloid,exbibits antioxidant properties and free radical scavenging capacity and exerts antidepressant-like effect.

Glucodigifucoside, a cardiac glycoside that can be isolated from digitalis seeds, is specifically cytotoxic to human renal adenocarcinoma cells.

Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.

Picroside III is a cyclic enol ether terpene glycoside isolated from the traditional Chinese medicine hu huang lian.Picroside III has the potential to repair intestinal mucosal damage and reduce intestinal inflammation in mice.

Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro.

Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotective efficacy by attenuation of ROS generated through oxidative stress by an increase in the concentration of antioxidant enzymes and sustain membrane integrity which leads to restoring the damage caused by tBHP. Bacoside A can able to inhibit the progression of Experimental Autoimmune Encephalomyelitis (EAE) may be by the inhibition of inflammatory cytokines and chemokine evolved during active EAE. Bacoside A also has vasorelaxation.

Martynoside is an active glycoside extracted from Rehmannia, with anti-estrogen, anticancer, cytotoxic, hematopoietic, antioxidant, and anti-metastatic properties. It increases IGFBP3 levels through the ER pathway.

Digoxigenin bisdigitoxoside (Bisdigoxigenin) is a digoxigenin metabolite with anticancer activity and cytotoxicity.

Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has anti-inflammatory, antinociceptive, hypoglycemic activities and plays protective role in sepsis-

Globularin has hypoglycaemic and hypolipidemic activities in normal and streptozotocin-induced diabetic rats.

Bacopaside V is a natural product

6-Feruloylcatalpol is a cycloartenolide glycoside discovered in Callicarpa nudiflora, suitable for biochemical experiments and drug synthesis research.

Bacopaside N2 is a natural product

Isothymusin( MIC= 200 microg/mL) exhibits inhibition activity against Mycobacterium tuberculosis. It ( IC50=7.7 microg/mL ) exhibits antioxidant activity against the radical scavenging ability of DPPH.

Sibirioside A is a natural product

Bacosine is a natural product for research related to life sciences. The catalog number is TN3479 and the CAS number is 198014-94-7.

2,7-Dihydroxy-2H-1,4-benzoxazin-3(4H)-one is a natural product of Scoparia, Scrophulariaceae. The catalog number is TN2744 and the CAS number is 69804-59-7. 2,7-Dihydroxy-2H-1,4-benzoxazin-3(4H)-one can be used as a reference standard.