Phellodendron

Phellamurin inhibits intestinal P-glycoprotein in a dose-dependent manner, there is a serious interaction occurred between Phellamurin with cyclosporin, to ensure the efficacy of cyclosporin, we suggest that the coadministration of Phellamurin or Phellode

Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits monoamine oxidase (IC50 4 micromolar for MAO-A and 62 for MAO-B).

1. Phellodendrine (Phallodendrin) has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.

Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the pot

Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 hippocampal neurons.

Oxypalmatine (8-Oxypalmatine) is a berberine-type alkaloid isolated from Phellodendron amurense that regulates breast cancer cell proliferation and apoptosis by inhibiting PI3K/AKT signaling and its efficacy in breast cancer-like organs.

D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability reduction and LDH release of the prim

Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.

6-Methylpiperidin-2-one is a piperidine derivative widely used in biochemical experiments and drug synthesis research.

Sinapaldehyde glucoside is a glucoside isolated from the bark of Ilex rotunda, with antioxidant and antimicrobial activities, inhibiting bacterial and fungal growth.

5,5'-Dimethoxylariciresinol is a natural product of Phellodendron, Rutaceae. The catalog number is TN3078 and the CAS number is 116498-58-9. 5,5'-Dimethoxylariciresinol can be used as a reference standard.

Methyl 3-O-feruloylquinate inhibits the activity of bacteria and viruses and to regulate immunity.

Kihadanin A is a natural product from Phellodendron amurense.

Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes.

Bourjotinolone A is a natural product of Phellodendron, Rutaceae. The catalog number is TN5943 and the CAS number is 6985-35-9. Bourjotinolone A can be used as a reference standard.

Dihydroniloticin shows cytotoxic activity against a HT-1080 human fibrosarcoma cell line( IC50 = 8.2 microM).

3Beta-acetoxy-eupha-7,25-dien-24(R)-ol is a natural product for research related to life sciences. The catalog number is TMA0683 and the CAS number is 1352001-09-2.

Demethyleneberberine chloride is a metabolite of berberine and belongs to the class of isoquinoline alkaloid derivatives. Demethyleneberberine chloride is a naturally occurring antioxidant with mitochondrial targeting properties that alleviates colitis in mice and suppresses inflammation by inhibiting the NF-κB pathway and modulating Th cell balance. Demethyleneberberine chloride exerts metabolic regulatory effects by activating lipid metabolism and related signaling pathways (AMPK) and can be used in research on non-alcoholic fatty liver disease (NAFLD).

Piscidinol A is toxic against the 4T1 and HEp2 cancer cell lines, the IC50 of 8.0 ± 0.03 and 8.4 ± 0.01 uM, respectively. It can inhibit NO production in mouse peritoneal macrophages with inhibitory ratios ranging from 39.8±7.7 to 68.2±4.5%.

Phellochin is a natural product of Phellodendron, Rutaceae. The catalog number is TN4762 and the CAS number is 115334-04-8. Phellochin can be used as a reference standard.

Methyl 5-O-feruloylquinate is a natural product of Phellodendron, Rutaceae. The catalog number is TN4534 and the CAS number is 154461-64-0. Methyl 5-O-feruloylquinate can be used as a reference standard.