Orobanchaceae

Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitric oxide radical-scavenging and vasodilative ones.

Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.

Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.

Monomelittoside (Danmelittoside) is a cycloaromatic terpene natural product derived from Stachys grandidentata (Labiatae).

Tubuloside A ( 8.6 microM) can inhibit D-galactosamine-induced death of hepatocytes. Tubuloside A has NO radical-scavenging activity, which possibly contributes to its anti-inflammatory effects.Tubuloside A shows stronger free radical scavenging activitie

Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B pathways.

1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respiratory chain function in mitochondria.

Rehmannioside D is a carotenoid glycoside that existed in the roots of Rehmannia glutinosa.

2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Acetylacteoside shows antiproliferative effects on aortic smooth muscle, indicates that it may ha

Melittoside is a natural phenolic glycoside found in the nectar of the Melitto genus. It has antioxidant, anti-inflammatory and antifungal activities, as well as research into its potential use in the treatment of various diseases, including cancer, diabetes and cardiovascular disease.

Purpureaside C is a phenolic glycoside with significant proinflammatory, immunomodulating and antimicrobial effects.

Digoxigenin, a therapeutic drug belonging to the group of cardiac glycosides, is widely used in the management of congestive heart failure and other cardiac diseases

Verbasoside (Decaffeoyl acteoside) is a phenylpropanoid isolated from the roots of Rehmannia glutinosa (Gaertn.) DC.

9-amino-CPT (Aminocamptothecin) is an inhibitor of topoisomerase I with potent anticancer activity.

Loganic acid 6′-O-β-D-glucoside (8-Epi-Loganic acid-6'-O-β-D-glucoside) is a natural product derived from Cistanche deserticola that inhibits LPS-induced NO and TNF-α production.

Ajugol (Leonuride) shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml).

Rehmannioside C is an iridoid glucoside. Rehmannioside C has been isolated from Radix Rehmanniae Praeparata[1].

4-Hydroxybenzyl alcohol (P-Methylolphenol) exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. 4-Hydroxybenzyl alcohol inhibit the development of new blood vessels by targeting multiple mechanisms of the angiogenic process, may as a promising candidate for the establishment of anti-angiogenic treatment strategies in cancer therapy.

Inexpensive starting material for chiral synthesis.

Jionoside A1 is isolated and purified from the roots of Rehmannia glutinosa. It displays dose-dependent immune-enhancement activity and possesses moderate neuroprotective activities on H2O2-treated SH-SY5Y cells.

Jionoside B1 is isolated from the roots of Jionoside (Gaertn.) and inhibits α-glucosidase.

8-Epiloganin (8-epi-Loganin) is a compound isolated from Pedicularis lasiophrys with anti-inflammatory activity. It inhibits the release of pro-inflammatory cytokines induced by LPS.

8-Epiloganic acid has antibacterial and antiviral effects.

6-O-p-Methoxycinnamoylcatalpol is a natural glycoside and magnololide, widely used in biochemical experiments and drug synthesis research.