1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced expression of inducible COX-2 at both the mRNA and the protein levels , downregulated the production and mRNA expression of the inflammatory cytokine IL-6. 3. alpha-Cyperone inhibited actin cytoskeleton polymerization induced by APEC-O78 through down regulating the expression of Nck-2, Cdc42 and Rac1.
Neonuezhenide is a phenolic compound isolated from Ligustrum officinale, which has strong antioxidant effects on free radical-induced hemolysis of red blood cells.
α-Viniferin known as 2-arylbenzofuran flavonoids, that are inhibitors of prostaglandin H2 synthetase. α-Viniferin has anti-Alzheimer's disease, anti-tuberculosis, anti-tumor, anti-inflammation, anti-diabetes and other pharmacological activitie
Beta-Rotunol is a natural product of Cyperus, Cyperaceae. The catalog number is TN3506 and the CAS number is 24405-57-0. Beta-Rotunol can be used as a reference standard.
Pyrogallol-phloroglucinol-6,6-bieckol (PPB) is a bioactive phlorotannin compound isolated from the brown alga Ecklonia cava that exerts potent anti-inflammatory and anti-atherogenic activities by inhibiting monocyte migration and macrophage differentiation toward inflammatory phenotypes. Pyrogallol-phloroglucinol-6,6-bieckol reduces monocyte-induced endothelial cell death and suppresses vascular smooth muscle cell proliferation and migration, contributing to vascular protection and potential therapeutic modulation of inflammatory vascular diseases.
Kobusone is a natural product of Cyperus, Cyperaceae. The catalog number is TN4395 and the CAS number is 24173-71-5. Kobusone can be used as a reference standard.
Kobophenol A is an oligostilbene natural product derived from plants with multi-target biological activities. Studies suggest that Kobophenol A may interfere with the interaction between ACE2 and the SARS-CoV-2 spike receptor-binding domain (RBD), potentially inhibiting viral entry. In addition, Kobophenol A has been reported to exhibit modulatory or inhibitory activity against Protein kinase C.