TN1542 |
Cycloheterophyllin
|
36545-53-6
|
98%
|
|
Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced oxidative stress and damage, and could be u...
|
TN1694 |
Gliotoxin
|
67-99-2
|
98%
|
|
Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signalin...
|
TN3383 |
α-Amyrin palmitate
|
22255-10-3
|
98%
|
|
alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats. alpha-Amyrin palmitate is a potent non-competitive inhibitor of chymotrypsin ...
|
T81447 |
PKItide
|
126370-52-3
|
98%
|
|
PKItide demonstrates an inhibitory concentration 50 (IC50) of 0.2 μM against cAMP-dependent protein kinase (cAMP-PK) [1].
|
T82984 |
Aplithianines A
|
|
98%
|
|
Aplithianines A effectively inhibits J-PKAcα with an IC50 value of 1 μM and displays higher potency against wild-type PKA, achieving an IC50 of 84 nM by competit...
|
T15669 |
KT5720
|
108068-98-0
|
98%
|
|
KT5720 is a cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase A (PKA) (Ki: 60 nM).
|
TN4277 |
Isocupressic acid
|
1909-91-7
|
98%
|
|
Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reprodu...
|
TP1351 |
Kemptide
|
65189-71-1
|
98%
|
|
Kemptide is a synthetic heptapeptide, acting as a substrate for cAMP-dependent protein kinase (PK).
|
TN4317 |
Isopedicin
|
4431-42-9
|
98%
|
|
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr...
|
TQ0072 |
Warangalone
|
4449-55-2
|
98%
|
|
Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with ...
|
T3060 |
Fasudil hydrochloride
|
105628-07-7
|
99.98%
|
|
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
|
T2205 |
Acefylline
|
652-37-9
|
99.95%
|
|
Acefylline (Theophylline-7-acetic acid), a stimulant drug of the xanthine chemical class, acts as an adenosine receptor antagonist. It is combined with diphenhyd...
|
T14064 |
8-Bromo-cGMP sodium
|
51116-01-9
|
99.91%
|
|
8-Bromo-cGMP sodium is a PKG activator, a membrane-permeable analog of cGMP. 8-Bromo-cGMP sodium has pain-relieving and vasodilatory effects, significantly inhib...
|
T6747 |
8-Bromo-cAMP sodium salt
|
76939-46-3
|
99.89%
|
|
8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase(PKA), but r...
|
T6680 |
Staurosporine
|
62996-74-1
|
99.87%
|
|
Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr,...
|
T6312 |
R547
|
741713-40-6
|
99.84%
|
|
R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kin...
|
T1606 |
Fasudil
|
103745-39-7
|
99.84%
|
|
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
|
T2851 |
Daphnetin
|
486-35-1
|
99.82%
|
|
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), an...
|
T14069 |
A-3 hydrochloride
|
78957-85-4
|
99.79%
|
|
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and c...
|
T0465 |
Ellagic acid
|
476-66-4
|
99.76%
|
|
Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the ...
|