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Schizophrenia Modeling
Schizophrenia is a severe psychiatric disorder characterized by hallucinations, delusions, and cognitive impairments. Experimental models include pharmacological induction using MK-801, PCP, or amphetamine (AMPH), as well as genetic models involving deletions of DISC1 or NRG1. These models are employed to study dopamine dysregulation, glutamate signaling abnormalities, and neurodevelopmental mechanisms.
Dizocilpine
Cited
T625977086-21-6
MK-801 (Dizocilpine (MK-801)) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.
- $35
Size
QTY
CitedDizocilpine Maleate
T332077086-22-7
Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membranes. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role.
- $32
Size
QTY
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