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Peptides
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- Tumor
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- Alangiaceae
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- Hydrolases,EC 3
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- Coronavirus (CoV) Proteins
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- Molecular Docking
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Schizophrenia Modeling
Schizophrenia is a severe psychiatric disorder characterized by hallucinations, delusions, and cognitive impairments. Experimental models include pharmacological induction using MK-801, PCP, or amphetamine (AMPH), as well as genetic models involving deletions of DISC1 or NRG1. These models are employed to study dopamine dysregulation, glutamate signaling abnormalities, and neurodevelopmental mechanisms.
Dizocilpine
T625977086-21-6
Dizocilpine (MK-801) is a selective non-competitive NMDA receptor antagonist with a Kd of 37.2 nM that exhibits anticonvulsant effects. It acts by binding to a site within the NMDA-associated ion channel, blocking the flow of Ca²⁺, and is commonly used to establish schizophrenia models.
- $35
Size
QTY
Dizocilpine Maleate
T332077086-22-7
Dizocilpine Maleate (MK-801 maleate) is a potent, selective, and non-competitive NMDA receptor antagonist with a Kd value of 37.2 nM. It is commonly used in the treatment of various neurodegenerative diseases in which NMDA receptors may be involved, and can also be used to induce schizophrenia models.
- $32
Size
QTY
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