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Cardiovascular System Disease ModelingHyperlipidemia Modeling
Hyperlipidemia is a major risk factor for atherosclerosis and cardiovascular events. Common models include high-fat, high-cholesterol diets (HFD) and genetically modified mice such as ApoE竅ｻ/竅ｻ or LDLR竅ｻ/竅ｻ strains to induce hypercholesterolemia and hypertriglyceridemia. These models are widely used to study lipid metabolism regulation and to screen lipid-lowering drugs.
Cholesterol
Cited
T076057-88-5
Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is widely found in the cell membranes of animals and is also used in the synthesis of several important hormones and bile acids.
- $45
Size
QTY
CitedArgatroban Monohydrate
T22246141396-28-3
Argatroban Monohydrate is a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.
- $33
Size
QTY
Argatroban Cited
T015574863-84-6
Argatroban (MCI-9038), a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.
- $33
Size
QTY
CitedMethylthiouracil
T030456-04-2
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
- $40
Size
QTY
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