Cholesterol is the primary sterol in mammals, accounting for approximately 20–25% of the plasma membrane structure. It plays a key role in regulating membrane fluidity, permeability, and protein function. As an endogenous agonist of estrogen-related receptor α (ERRα), cholesterol is widely involved in metabolic regulation and serves as a precursor for the synthesis of hormones and bile acids. It is commonly used in experimental models of hyperlipidemia.

Argatroban is a specific thrombin inhibitor and a non-heparin anticoagulant that effectively prevents thrombus formation and is commonly used to establish thrombolysis models.

Tyloxapol is an alkyl aryl polyether alcohol-type nonionic liquid polymer used as a surfactant stabilizer. It is commonly used to induce hyperlipidemia models in animals.

Argatroban Monohydrate is a selective thrombin inhibitor and a non-heparin anticoagulant that effectively prevents thrombosis. It is commonly used in thrombolysis model studies.

Methylthiouracil is a thiourea-class antithyroid agent that inhibits the synthesis of thyroid hormones and is commonly used to treat hyperthyroidism. Studies have shown that Methylthiouracil can also suppress the production of TNF-α and IL-6, as well as inhibit the activation of NF-κB and ERK1 2. It can be used to induce hyperlipidemia and neurological disorder models.