Home Tools
Log in
Cart

Protease-activated Receptor

Protease-activated receptors (PAR) are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular domain. They are highly expressed in platelets, and also on endothelial cells, myocytes and neurons.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T7380 Protease-Activated Receptor-4 245443-52-1
Protease-Activated Receptor-4
Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy
T7573 TFLLR-NH2 197794-83-5
TFLLR-NH2
TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).
T4186 AC-264613 1051487-82-1 98%
AC-264613
AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin...
T7496 Thrombin Receptor Activator for Peptide 5 (TRAP-5) 141685-53-2 98%
Thrombin Receptor Activator for Peptide 5 (TRAP-5)
Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in c...
T7623L PAR-4 Agonist Peptide, amide acetate T7623L 98%
PAR-4 Agonist Peptide, amide acetate
PAR-4 Agonist Peptide, amide acetate is an agonist of proteinase-activated receptor-4 (PAR-4).
T7013 Vorapaxar 618385-01-6 99.93%
Vorapaxar
Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).
T8917 PAR-2-IN-1 1690176-75-0 99.79%
PAR-2-IN-1
PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.
T41190 AY 77 1835734-92-3 99.7%
AY 77
AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ...
T3098 Vorapaxar sulfate 705260-08-8 99.46%
Vorapaxar sulfate
Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.
T7740 Protease-Activated Receptor-4 diTFA T7740 99.42%
Protease-Activated Receptor-4 diTFA
Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonist
T2370 AC-55541 916170-19-9 99.35%
AC-55541
AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobiliz...
TP1904L FSLLRY-NH2 TFA(245329-02-6 free base) TP1904L 99.32%
FSLLRY-NH2 TFA(245329-02-6 free base)
FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR...
T63966 BMS-986141 1478711-48-6 99.11%
BMS-986141
BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614 exhibi...
T21699L VKGILS-NH2 Acetate T21699L 98.83%
VKGILS-NH2 Acetate
VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.
T12870 SCH79797 dihydrochloride 1216720-69-2 98.58%
SCH79797 dihydrochloride
SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihyd...
T38852L TRAP-6 amide acetate 98.55%
TRAP-6 amide acetate
TRAP-6 amide acetate is a PAR-1 thrombin receptor agonist peptide[1].
TP1046L PAR-2 Activating Peptide acetate TP1046L 98.5%
PAR-2 Activating Peptide acetate
PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).
TQ0012 AZ3451 2100284-59-9 98.44%
AZ3451
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
TP1046 SLIGRL-NH2 171436-38-7 98.29%
SLIGRL-NH2
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus.
T1986 Atopaxar 751475-53-3 98.25%
Atopaxar
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Corona...
Protease-Activated Receptor-4
T7380
Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy
TFLLR-NH2
T7573
TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).
AC-264613
T4186
AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin...
Thrombin Receptor Activator for Peptide 5 (TRAP-5)
T7496
Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in c...
PAR-4 Agonist Peptide, amide acetate
T7623L
PAR-4 Agonist Peptide, amide acetate is an agonist of proteinase-activated receptor-4 (PAR-4).
Vorapaxar
T7013
Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).
PAR-2-IN-1
T8917
PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.
AY 77
T41190
AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ...
Vorapaxar sulfate
T3098
Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.
Protease-Activated Receptor-4 diTFA
T7740
Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonist
AC-55541
T2370
AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobiliz...
FSLLRY-NH2 TFA(245329-02-6 free base)
TP1904L
FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR...
BMS-986141
T63966
BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614 exhibi...
VKGILS-NH2 Acetate
T21699L
VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.
SCH79797 dihydrochloride
T12870
SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihyd...
TRAP-6 amide acetate
T38852L
TRAP-6 amide acetate is a PAR-1 thrombin receptor agonist peptide[1].
PAR-2 Activating Peptide acetate
TP1046L
PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).
AZ3451
TQ0012
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
SLIGRL-NH2
TP1046
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus.
Atopaxar
T1986
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Corona...
1 2
TargetMol