NADPH

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent. It is used by all forms of cellular life.NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the presence of an additional phosphate group on the 2' position of the ribose ring that carries the adenine moiety. This extra phosphate is added by NAD+ kinase and removed by NADP+ phosphatase.

Cat. No.	Product name	CAS No.	Purity
TN3806	Dehydroglyasperin C	199331-35-6	98%
TN3806	Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
T16361	Nucleocidin	24751-69-7	98%
T16361	Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein.
T39635	Obafistat	2160582-57-8	98%
T39635	Obafistat is a potent inhibitor of aldo-keto reductase AKR1C3 with an IC50 of 1.2 nM for human AKR1C3 (patent WO2017202817A1, example 4).
T38684	AKR1C3-IN-4	1284180-11-5	98%
T38684	AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant...
T61316	HTS07545	118666-03-8	98%
T61316	HTS07545 is a potent sulfide:quinone oxidoreductase inhibitor (IC50: 30 nM).HTS07545 reduces the rate of hydrogen sulfide (H2S) decomposition.HTS07545 has been u...
T15429	GSK2194069	1332331-08-4	98%
T15429	GSK2194069 is an active β-keto reductase (KR)-specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released C...
T0342	Carvedilol phosphate hemihydrate	610309-89-2	98%
T0342	Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intri...
T1314	Triclosan	3380-34-5	98%
T1314	Triclosan is an antibacterial and antifungal agent.
T67950	S19-1035		98%
T67950	S19-1035 is a highly potent and specific aldo-keto reductase 1C3 (AKR1C3) inhibitor. S19-1035 inhibits AKR1C3 with an IC 50 value of 3.04 nM. S19-1035 can be use...
T7374	2-HBA	131359-24-5	98%
T7374	2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
T4529	ASP-9521	1126084-37-4	98%
T4529	ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
TN2126	Quercetin-3-O-glucose-6''-acetate	54542-51-7	98%
TN2126	Quercetin-3-O-glucose-6''-acetate is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
T4359	VAS2870	722456-31-7	98%
T4359	VAS2870 is an inhibitor of NADPH oxidase (NOX).
T7191	Diphenyleneiodonium chloride	4673-26-1	98%
T7191	Diphenyleneiodonium chloride(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 µM, respectively),and displays broad-spectrum bacte...
T7406	AKR1C3-IN-1	327092-81-9	98%
T7406	AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
T0441	Pasiniazid	2066-89-9	98%
T0441	Pasiniazid is an anti-TB and anti-leprosy drug.
T8408	GKT136901	955272-06-7	98%
T8408	GKT136901 is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
T15433	GSK2795039	1415925-18-6	98%
T15433	GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2...
T10353	APX-115 free base	1270084-92-8	98%
T10353	APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase （Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox...
T16342	KL1333	1800405-30-4	98%
T16342	KL1333 enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subseque...