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Metabolism NADPH

NADPH

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent. It is used by all forms of cellular life.NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the presence of an additional phosphate group on the 2' position of the ribose ring that carries the adenine moiety. This extra phosphate is added by NAD+ kinase and removed by NADP+ phosphatase.
Cat No. product name
T0342 Carvedilol phosphate Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intr...
T0441 Pasiniazid Pasiniazid is an anti-TB and anti-leprosy drug.
T0447 Carvedilol Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intr...
T0809 Dicumarol Dicumarol is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a com...
T0816 Acetohexamide Acetohexamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwa...
T1079 Metronidazole Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
T1314 Triclosan Triclosan is an antibacterial and antifungal agent.
T14151 AKR1C1-IN-1 AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).
T15433 GSK2795039 GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase ...
T1558 ResveratrolHOT Resveratrol is a polyphenolic phytoalexin with antioxidant and chemopreventive activities. It has a wide spectrum of targets including COX, SIRT, LOC, etc.
T1609 NAD+ NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and i...
T16361 Nucleocidin Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein.
T4359 VAS2870 VAS2870 is a NADPH oxidase (NOX) inhibitor.
T4529 ASP9521 ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
T6391 Acetovanillone Apocynin is a specific NADPH-oxidase inhibitor (IC50: 10 μM).
T7149 S29434 S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).
T7374 2-HBA 2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
T7406 AKR1C3-IN-1 AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
TN3806 Dehydroglyasperin C Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemo...
Carvedilol phosphate
T0342CAS 610309-89-2
Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intr...
Pasiniazid
T0441CAS 2066-89-9
Pasiniazid is an anti-TB and anti-leprosy drug.
Carvedilol
T0447CAS 72956-09-3
Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intr...
Dicumarol
T0809CAS 66-76-2
Dicumarol is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a com...
Acetohexamide
T0816CAS 968-81-0
Acetohexamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwa...
Metronidazole
T1079CAS 443-48-1
Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
Triclosan
T1314CAS 3380-34-5
Triclosan is an antibacterial and antifungal agent.
AKR1C1-IN-1
T14151CAS 4906-68-7
AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).
GSK2795039
T15433CAS 1415925-18-6
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase ...
Resveratrol HOT
T1558CAS 501-36-0
Resveratrol is a polyphenolic phytoalexin with antioxidant and chemopreventive activities. It has a wide spectrum of targets including COX, SIRT, LOC, etc.
NAD+
T1609CAS 53-84-9
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and i...
Nucleocidin
T16361CAS 24751-69-7
Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein.
VAS2870
T4359CAS 722456-31-7
VAS2870 is a NADPH oxidase (NOX) inhibitor.
ASP9521
T4529CAS 1126084-37-4
ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
Acetovanillone
T6391CAS 498-02-2
Apocynin is a specific NADPH-oxidase inhibitor (IC50: 10 μM).
S29434
T7149CAS 874484-20-5
S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).
2-HBA
T7374CAS 131359-24-5
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
AKR1C3-IN-1
T7406CAS 327092-81-9
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
Dehydroglyasperin C
TN3806CAS 199331-35-6
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemo...