T26644 |
Apomine
|
126411-13-0
|
98%
|
|
Apomine is an inhibitor of HMG-CoA-reductase. Apomine promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo. Apomin...
|
T11572 |
HMG499
|
2416941-68-7
|
98%
|
|
HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC 50 of 0.41 μM. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cho...
|
T10767 |
Cerivastatin sodium
|
143201-11-0
|
98%
|
|
Cerivastatin sodium is a synthetic lipid-lowering agent and a highly potent and orally active HMG-CoA reductase inhibitor (Ki: 1.3 nM). It also inhibits the prol...
|
T10070 |
2'-Ethyl Simvastatin
|
79902-42-4
|
98%
|
|
2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.
|
TN1438 |
Beta-Amyrin acetate
|
1616-93-9
|
98%
|
|
beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, ...
|
T10324 |
Anhydrosimvastatin
|
210980-68-0
|
|
|
Anhydrosimvastatin is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.
|
T1664 |
Meglutol
|
503-49-1
|
|
|
Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic st...
|
T0683 |
Mevastatin
|
73573-88-3
|
97.96%
|
|
Mevastatin is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials....
|
TN1733 |
Hesperetin 7-O-glucoside
|
31712-49-9
|
98.1%
|
|
Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition...
|
T1510 |
Rosuvastatin calcium
|
147098-20-2
|
98.85%
|
|
Rosuvastatin, a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity.
|
T0672 |
Pravastatin sodium
|
81131-70-6
|
99.08%
|
|
Pravastatin sodium, an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.
|
T1487 |
Fluvastatin sodium
|
93957-55-2
|
99.46%
|
|
Fluvastatin sodium, a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.
|
T3698 |
Alpha-Asarone
|
2883-98-9
|
99.59%
|
|
Alpha-Asarone is a psychoactive compound with antidepressant-like activity in mice.
|
T2534 |
Pitavastatin calcium
|
147526-32-7
|
99.71%
|
|
Pitavastatin is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and hum...
|
T1207 |
Lovastatin
|
75330-75-5
|
99.72%
|
|
Lovastatin is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.
|
T1676 |
Rosuvastatin
|
287714-41-4
|
99.75%
|
|
Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversio...
|
T4717 |
25-Hydroxycholesterol
|
2140-46-7
|
99.78%
|
|
25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase ...
|
T6450 |
Clinofibrate
|
30299-08-2
|
99.84%
|
|
Clinofibrate(IC50 of 0.47 mM), a lipid-lowering agent, inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR). It is utilized to control high cholesterol an...
|
T3116 |
Atorvastatin hemicalcium salt
|
134523-03-8
|
99.89%
|
|
Atorvastatin hemicalcium salt, an effective HMG-CoA reductase inhibitor (IC50 = 8 nM), is utilized as a cholesterol-lowering medication.
|
T0687 |
Simvastatin
|
79902-63-9
|
99.95%
|
|
Simvastatin is a HMG-CoA Reductase Inhibitor. The mechanism of action of simvastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor.
|