T20887 |
Atorvastatin Sodium
|
134523-01-6
|
98%
|
|
Atorvastatin sodium is a competitive inhibitor of HMG-CoA reductase and increases the expression of low density lipoprotein (LDL) receptors on hepatocytes. atorv...
|
T10767 |
Cerivastatin sodium
|
143201-11-0
|
98%
|
|
Cerivastatin sodium is a synthetic lipid-lowering agent and a highly potent and orally active HMG-CoA reductase inhibitor (Ki: 1.3 nM). It also inhibits the prol...
|
T10070 |
2'-Ethyl Simvastatin
|
79902-42-4
|
98%
|
|
2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.
|
T11572 |
HMG499
|
2416941-68-7
|
98%
|
|
HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC 50 of 0.41 μM. HMG499 can eliminate statins-induced accumulation of HMGCR, lower serum ch...
|
T6994 |
SR12813
|
126411-39-0
|
98%
|
|
SR-12813 is a pregnane X receptor (PXR) agonist.
|
T0687 |
Simvastatin
|
79902-63-9
|
98%
|
|
Simvastatin is a HMG-CoA Reductase Inhibitor. The mechanism of action of simvastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor.
|
T6450 |
Clinofibrate
|
30299-08-2
|
98%
|
|
Clinofibrate(IC50 of 0.47 mM), a lipid-lowering agent, inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR). It is utilized to control high cholesterol an...
|
TN1438 |
Beta-Amyrin acetate
|
1616-93-9
|
98%
|
|
beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, ...
|
T3698 |
Alpha-Asarone
|
2883-98-9
|
98%
|
|
Alpha-Asarone is a psychoactive compound with antidepressant-like activity in mice.
|
T13131 |
Tert-Buthyl Pitavastatin
|
586966-54-3
|
98%
|
|
tert-Buthyl Pitavastatin is Pitavastatin metabolite. Pitavastatin is a potent inhibitor of HMG-CoA reductase.
|
T1487 |
Fluvastatin sodium
|
93957-55-2
|
98%
|
|
Fluvastatin sodium, a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.
|
T0672 |
Pravastatin sodium
|
81131-70-6
|
98%
|
|
Pravastatin sodium, an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.
|
T12092 |
Monacolin J
|
79952-42-4
|
98%
|
|
Monacolin J is a cholesterol biosynthesis inhibitor.
|
TN1733 |
Hesperetin 7-O-glucoside
|
31712-49-9
|
98%
|
|
Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition...
|
T25285 |
Dalvastatin
|
132100-55-1
|
98%
|
|
Dalvastatin is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepatic HMG-CoA reduc...
|
T0683 |
Mevastatin
|
73573-88-3
|
98%
|
|
Mevastatin is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials....
|
T14342 |
Atorvastatin lactone
|
125995-03-1
|
98%
|
|
Atorvastatin lactone is a prodrug of atorvastatin. Atorvastatin is an orally active inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.
|
T1676 |
Rosuvastatin
|
287714-41-4
|
98%
|
|
Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversio...
|
T26644 |
Apomine
|
126411-13-0
|
98%
|
|
Apomine is an inhibitor of HMG-CoA-reductase. Apomine promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo. Apomin...
|
T10324 |
Anhydrosimvastatin
|
210980-68-0
|
98%
|
|
Anhydrosimvastatin is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.
|