vb1

Thiamine hydrochloride (Vitamin B1) is an essential micronutrient and a cofactor for many central metabolic enzymes.

Anti-CD44 Antibody (VB6-008 antibody) is an IgG1 monoclonal antibody targeting CD44, useful for tumor research.

VB1-050 is a highly specialized fully human monoclonal antibody target the human solute carrier family 2 member 8 protein, also known as glucose transporter 8 or GLUT8, inhibition of hexose transport and receptor-mediated internalization across various preclinical experimental models of breast, liver, prostate, and colon cancers where the target antigen exhibits preferential expression compared to limited reactivity in normal tissues.

VB1080 (compound 12) is a potent PIM inhibitor with IC50 values of 69.5 µM for PIM1, 4996 µM for PIM2, and 9.88 µM for PIM3. Additionally, VB1080 exhibits cytotoxic properties and possesses anthelmintic activity.

VB124 is an orally active, potent and selective MCT4 inhibitor. VB124 blocked lactate import (IC50 value of 8.6 nM) and export (IC50 value of 19 nM) in MDA-MB-231 cells. VB124 is selective for MCT4 over MCT1 and shows minimal MCT1 inhibitory activity in MCT1-expressing BT20 cells (IC50 value of 24 μM).

αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.

Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA, and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 (Cobalamin) deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.

αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).

DV-B-120 is a competitive inhibitor of the dengue virus (DENV). It inhibits the NS2B-NS3 protease, effectively targeting DENV-1, DENV-2, DENV-3, and DENV-4 with IC50 values of 5.35, 7.39, 10.49, and 8.58 μM, respectively. DV-B-120 exerts its antiviral effects by inhibiting DENV replication.

VB 11328 is a biochemical.