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By Target- TSH Receptor
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Results for "
thyrotropin receptor (tshr)
" in TargetMol Product Catalog- Inhibitors & Agonists9
- Recombinant Protein2
- Antibody Products1
VA-K-14 hydrochloride
VAK14 Hydrochloride, VA K 14 HCl, VA-K-14 HCl, VAK14 HCl
T290871171341-19-7In house
VA-K-14 hydrochloride(VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.
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ML-109 
Cited
T120731186649-91-1
ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)
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CitedD3-βArr
NCGC00379308
T5383662164-09-2
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
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NCGC00229600
T121921338824-20-6
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.
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TSHR antagonist S37
T132161217616-61-9
TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).
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TSHR antagonist S37a
T132172143452-20-2
TSHR antagonist S37a is a selective antagonist of thyrotropin receptor (TSHR), with potential for the treatment of Graves' orbitopathy.
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ML224
NCGC00242364, ANTAG3
T161061338824-21-7
ML224 (NCGC00242364) is a TSHR antagonist for the treatment of Graves' orbital disease and Graves' hyperthyroidism.
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Org41841
Org-41841
T16403301847-37-0
Org41841 is an agonist of luteinising hormone chorionic gonadotropin receptor and thyroid stimulating hormone receptor (EC50s: 0.2 and 7.7 μM, respectively) and can be used to study hyperthyroidism.
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TSHR antagonist S37b
T382262143452-22-4
TSHR antagonist S37b, the less potent enantiomer of TSHR antagonist S37a, exhibits minimal efficacy in inhibiting the thyrotropin receptor (TSHR). It is utilized in thyroid function research[1].
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