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Results for "

tetrahydrofolate

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    19
    TargetMol | Inhibitors_Agonists
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Trimethoprim
NSC-106568, NIH 204, BW 56-72
T1153738-70-5
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.
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5-Methyltetrahydrofolate triglutamate
5-Me-Thf(glu)3
T2946150998-20-4
5-Methyltetrahydrofolate triglutamate is a form of folic acid.
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Calcium N5-methyltetrahydrofolate
NSC173328
T759826560-38-3
Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers
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5-Methyltetrahydrofolic acid
5-Methyl THF
T13516134-35-0
5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivative of tetrahydrofolate, serving as the predominant natural dietary folate and the principal form of folate found in plasma and cerebrospinal fluid.
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Methotrexate disodium
T80037413-34-5
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
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7-Hydroxymethotrexate
NSC 380963, NSC-380963, NSC380962, NSC380963, NSC 380962, NSC-380962
T203395939-37-7
7-Hydroxymethotrexate is the major metabolite of Methotrexate.Methotrexate is an inhibitor of folic acid, inhibiting dihydrofolate reductase, which prevents the conversion of folic acid to tetrahydrofolate, and inhibiting DNA synthesis.Methotrexate is also an inhibitor of metabolism.
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5-Monobutyl methotrexate
NSC-305986, NSC305986, NSC 305986, gamma-Mbmtx
T2498566147-31-7
5-Monobutyl methotrexate is an antineoplastic antimetabolite with immunosuppressant properties. It is a TETRAHYDROFOLATE DEHYDROGENASE inhibitor and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component
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Aminopterin N-hydroxysuccinimide ester
Nhs-aminopterin,N-Hydroxysuccinimide aminopterin
T2507998457-88-6
Aminopterin N-hydroxysuccinimide ester is an antineoplastic agent with immunosuppressive properties. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrof
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6-8 weeks
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Emofolin sodium
NSC139490, MeTHHF disodium, NSC-139490, NSC 139490
T2537452386-42-2
Emofolin sodium is the sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity,which competes for the folate binding site of the enzyme dihydrofolate reductase, resulting in inhibition of tetrahydrofolate synthesis, deple
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Pralatrexate, (R)-
T259801320211-70-8
Pralatrexate, (R)- is a folate analog dihydrofolate reductase (DHFR) inhibitor exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. Pralatrexate selectively enters cells expressing RFC-1; intr
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10-14 weeks
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Pralatrexate, (S)-
T259811320211-69-5
Pralatrexate, (S)- is a folate analog dihydrofolate reductase (DHFR) inhibitor exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. Pralatrexate selectively enters cells expressing RFC-1; intr
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Levomefolate magnesium
L-Methylfolate magnesium
T327051429498-11-2
Levomefolate magnesium is the magnesium salt of the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma. It is transported across th
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Tetrahydrofolic acid trihydrochloride
L-Tetrahydrofolic acid trihydrochloride, L-5,6,7,8-Tetrahydrofolic acid trihydrochloride, (6R,S)-5,6,7,8-Tetrahydrofolic Acid hydrochloride
T35413150731-85-4
Tetrahydrofolic acid trihydrochloride (L-5,6,7,8-Tetrahydrofolic acid trihydrochloride) is a biologically active vitamin B9 derivative, a receptor for free formaldehyde, and an effective suicide substrate for mushroom tyrosinase, inhibiting indole ethylamine methylation by methyl-tetrahydrofolate.
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N-(4-Aminobenzoyl)-L-glutamic Acid (hydrate)
T37998
N-(4-Aminobenzoyl)-L-glutamic acid is an oxidation product and a metabolite of tetrahydrofolate.1Levels of N-(4-aminobenzoyl)-L-glutamic acid are increased in the plasma of mice fed a high folic acid-containing diet.2 1.Reed, L.S., and Archer, M.C.Oxidation of tetrahydrofolic acid by airJ. Agric. Food Chem.28(4)801-805(1980) 2.Burton, M.A., Antoun, E., Penailillo, R.S., et al.Folic acid induces intake-related changes in the mammary tissue transcriptome of C57BL/6 miceNutrients12(9)2821(2020)
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Methotrexate di-n-butyl ester
T6917750602-77-2
Methotrexate di-n-butyl ester is an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofoltae dehydrogenase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
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6-8 weeks
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Methotrexate diethyl ester
T6925743170-88-3
Methotrexate diethyl ester is an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofoltae dehydrogenase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
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6-8 weeks
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10 FTHF disodium
10-Formyltetrahydrofolate disodium, 10-Formyltetrahydrofolic acid disodium, 10FTHF disodium
T73731914800-65-0
10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate, a formyl donor in anabolism, involved in the synthesis of purine compounds.
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Sarcosine oxidase
T761319029-22-5
Sarcosine oxidase (SAO) catalyzes the oxidative demethylation of sarcosine, producing glycine, H2O2, and 5,10-CH2-tetrahydrofolate, substances commonly utilized in biochemical reactions [1].
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7-10 days
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Aminopterin sodium
NSC739,NSC 739 [as the base],NSC-739
T7730L58602-66-7
Aminopterin sodium is an antineoplastic agent with immunosuppressive properties. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrofolate reductase effe
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6-8 weeks
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