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Cat No. | Product Name | Synonyms | Targets |
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T22408 | Proflavine | 3,6-Diaminoacridine | Antibacterial |
Proflavine (3,6-Diaminoacridine) (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria and is a topical antiseptic used mainly in wound dressings. | |||
T0438 | Proflavine Hemisulfate | 3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate | Others , Potassium Channel , DNA , Thrombin , Antibacterial , Autophagy |
Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and a... | |||
T5585 | AM-92016 hydrochloride | Potassium Channel | |
AM-92016 is a specific blocker of rectifier potassium current. AM-92016 delays rectifier potassium channel and repolarizes the membrane thereby restricting the duration of the nerve impulse. | |||
T22745 | DPO-1 | Potassium Channel | |
DPO-1 is a blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels | |||
T27205 | DPI 201-106 | DPI-201-106 | Sodium Channel |
DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delayed rectifier potassium currents. | |||
T7505 | Azimilide Dihydrochloride | NE-10064 Dihydrochloride | Potassium Channel |
Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr) components of the delayed rectifier potassium current | |||
T31011 | Coralyne chloride | Topoisomerase | |
Coralyne Chloride is a molecular rectifier based on fluorescent DNA, which is constructed into DNA double-stranded bodies by site-specific insertion. | |||
T3574 | Sematilide hydrochloride | CK-1752A,CK-1752,Sematilide HCl | Potassium Channel |
Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the ... | |||
T6476 | Dofetilide | UK 68789,UK-68798,Tikosyn | Potassium Channel |
Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ik... | |||
T15555 | IK1 inhibitor PA-6 | Potassium Channel | |
IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse KIR2.x currents). | |||
T22662 | Chromanol 293B | Others | |
slow delayed rectifier K+ current (IKs) blocker | |||
T24948 | VU625 | VU007625,VU 625,VU 007625,VU-625,VU-007625 | |
VU625 is an effective inhibitor of Aedes aegypti inward rectifier potassium channels. | |||
T70194 | AM92016 | ||
AM92016 is a specific blocker of the time dependent delayed rectifier potassium current. AM92016 does not show any β-adrenoceptor blocking activity. | |||
T5336L | Zacopride | Racemic zacopride | |
Zacopride is a selective agonist of inward rectifier potassium current (I K1) channel, inhibiting ventricular arrhythmias without affecting atrial arrhythmias. | |||
T15460 | Halofantrine hydrochloride | WR-171669,SKF-102886 | Others |
Halofantrine hydrochloride is a blocker of delayed rectifier potassium current. Halofantrine hydrochloride also via the inhibition of the human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial agent. | |||
T14189 | Almokalant | H 234/09 | Potassium Channel |
Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker. And it inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current. | |||
T80510 | Tertiapin-RQ | Potassium Channel | |
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1]. | |||
T61685 | Ibutilide | ||
Ibutilide (U70226E free base) is a potent antiarrhythmic compound that extends the action potential duration. It effectively blocks the rapidly activating delayed rectifier potassium current (I Kr ) in AT-1 cells [1]. | |||
T17240 | VU041 | Others | |
VU041 is an inhibitor of Anopheles gambiae and Aedes aegypti inward rectifier potassium 1 channels (IC50: 2.5 μM and 1.7 μM, respectively). VU041 inhibits appreciably is mammalian Kir2.1 (IC50: 12.7 μM) and has less inhi... | |||
TP2114 | Tertiapin-Q | ||
A high affinity blocker for inward-rectifier K+ channels, this compound is a stable derivative of the bee venom toxin tertiapin. Binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with high affinity (Ki values are... | |||
T36740 | Guanosine 5’-diphosphate (sodium salt hydrate) | ||
Guanosine 5’-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5’-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 μM) activates sulfonylurea receptor 2B (SUR... | |||
T80426 | Jingzhaotoxin-IX | Sodium Channel | |
Jingzhaotoxin-IX is a C-terminally amidated peptide neurotoxin consisting of 35 amino acid residues. It inhibits both tetrodotoxin-resistant and tetrodotoxin-sensitive isoforms of voltage-gated sodium channels, as well a... | |||
T83749 | Tertiapin LQ TFA | TPNLQ | |
Tertiapin LQ, a peptide derivative of honeybee venom peptide tertiapin, acts as an inhibitor of inwardly rectifying potassium (Kir) channels. Specifically, it targets and inhibits heteromultimeric potassium channels, inc... |
Cat No. | Product Name | Synonyms | Targets |
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T8040 | Cholesterol myristate | Cholesteryl myristate,Cholesteryl tetradecanoate | Others , Potassium Channel , GABA Receptor , Endogenous Metabolite , AChR |
Cholesterol myristate (Cholesteryl myristate) is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as GABAA receptor, the nicotinic acetylcholine receptor... | |||
T4A2458 | Resibufogenin | Bufogenin,Recibufogenin | Others |
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff... | |||
TN3636 | Chlorahololide C | Potassium Channel | |
Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with the IC(50) value of 3.6 +/- 10.1 mu M. |
Cat No. | Product Name | Species | Expression System |
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TMPH-03066 | PatA Protein, Nostoc sp., Recombinant (His & Myc) | Nostoc sp. | E. coli |
Involved in the targeting and/or fusion of transport vesicles to their target membrane. Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters. Essential for fast... | |||
TMPH-01698 | MORC4 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled wit... | |||
TMPH-01697 | MORC3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the kidney. Contributes to the regulation of the ... |