radiolabeled

D-Lysine is the D-isomer of L-Lysine, prepared by chemical racemization and microbial asymmetric degradation of L-Lysine.D-Lysine reduces renal uptake of radiolabeled peptides and decreases nephrotoxicity.

Dotanoc is a ligand to make gallium Ga 68-DOTANOC, which is a gallium Ga 68-radiolabeled analog of somatostatin.

ω-Conotoxin MVIIC TFA is a peptide and neurotoxin with 26 residues that preferentially blocks P-type and Q-type Ca ++ currents by binding with high affinity to voltage-sensitive neuronal Ca ++ channels (VGCCs) and can be radiolabeled and used in immunoprecipitation assays.

WL12 is a peptide that targets and binds specifically to programmed death ligand 1 (PD-L1). It can be radiolabeled with various radionuclides to produce radiotracers, enabling the evaluation of PD-L1 expression in tumors [1].

DOTA-JR11, a somatostatin receptor 2 (SSTR2) antagonist, can be radiolabeled with 68Ga and is used for paired imaging in neuroendocrine tumor (NET) studies [1].

NODAGA-LM3 TFA, a SSTR2 antagonist, can be radiolabeled with ^68Ga for PET imaging applications, particularly in the visualization of SSTR-positive paragangliomas [1] [2].

Tyr3-Octreotate acetate is a somatostatin analogue with a high tumor uptake rate that can be labeled with radioactive metals, thus exhibiting antitumor activity. It is utilized in the synthesis and study of radiolabeled conjugate drugs (RDC).

HER2-targeted peptide H6F is a molecule designed to bind to HER2 and target breast cancer cells, characterized by the amino acid sequence YLFFVFER. It can conjugate with the bifunctional chelator hydrazinonicotinamide (HYNIC) for binding with 99mTc for radiolabeling purposes. Single-photon emission computed tomography (SPECT) imaging demonstrates that the radiolabeled HER2-targeted peptide H6F specifically accumulates in HER2-positive MDA-MB-453 tumor-bearing mouse models. This peptide is useful for studies in tumor molecular imaging.

DOTA-Octreotide TFA consists of the chelating agent DOTA and Octreotide. It is utilized in cancer research through its ability to bind with radioactive elements and is also employed in the synthesis and study of radiolabeled conjugate drugs (RDC).