protectant

Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.

Ectoine (L-Ectoine) is an osmoprotectant in a variety of microorganisms including halophilic and heterotrophic bacteria and non-halophilic bacteria such as the Streptomyces species, as well as E.coli.

Neuroprotectant-7 is a neuroprotectant for Alzheimer's disease. It displays significant neuroprotection and antioxidative properties. It also can cross the blood-brain barrier.

Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).

D-Cysteine, the D-isomer of cysteine, is a powerful inhibitor of E. coli growth and is mediated by D-amino acid oxidase to produce H2S, serving as a neuroprotective agent against cerebellar ataxia. Additionally, D-cysteine can inhibit the growth and cariogenicity of a two-species biofilm formed by Streptococcus mutans and Streptococcus hemoglobin.

CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1 expression.CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress.

1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. 3. Negletein shows a comparable redox-active potential, and it (50 μM, 4 h) can activate Nrf2. 4. Negletein shows significant antimicrobial activity. 5. Negletein has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice.6. Negletein has anti- Alzheimer's disease activity, it inhibits the iron-dependent formation of ROS and also blocks the iron-induced oligomerization of amyloid beta 42 in vitro. 7. Negletein (IC50: 3.89 +/- 0.39 microM) exhibits potent inhibitory activity against nuclear factor of activated T cells (NFAT) transcription factor.

Benthiazole (Superdavloxan) is a broad-spectrum seed protectant that is effective against soil- and seed-borne fungal or bacterial diseases.

trans-Urocanic Acid ((E)-Urocanic acid), a compound predominantly distributed in the hippocampus and prefrontal cortex, is an isomer of cis-UCA, an epidermal UV-protectant, which enhances the stability of tenofovir eplerenomide in long-acting HIV applications. trans-Urocanic acid potently modulates immune trans-urocanic acid effectively modulates immune function, inhibits human natural killer cell activity in vitro, and can be used in Alzheimer's disease research.

Ornoprostil, a prostaglandin E1 analogue, acts as a mucosal protectant.

Isoprothiolane is a foliar spray fungicide with eradicant and protectant activities against fungal diseases of rice plant caused by Pyvioutavia oryzae Cav.

Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium against acid injury. It can bind to exosite II of thrombin (KD = ~1.4 μM) and inhibit its catalytic activity (IC50 = 4.5 μM) and, as such, has been used as a surrogate for heparin. Furthermore, SOS has been shown to inhibit tumor growth in mouse melanoma and lung carcinoma models by preventing fibroblast growth factor 2 (FGF-2) binding to endothelial cells and also by removing any pre-bound FGF-2 from these cells (IC50 = ~2 μg/ml).

Sucralfate is a gastrointestinal protectant that includes sucrose octasulfate . Sucralfate protects gastric epithelial cells against acid- and pepsin-induced damage. Sucrose hexasulfate is a polysulfated disaccharide that is used as a reference standard for sucralfate.

Carboxin (Kisvax) appears as off-white crystals. Systemic fungicide and seed protectant.

Valienamine, an alpha-glucosidase inhibitor, is the crucial functional component of several natural glycosidase inhibitors, such as the crop protectant validamycin A and the antidiabetic agent acarbose [1].

Meptyldinocap (2,4-DNOPC) functions as an innovative fungicide against powdery mildew (Erysiphe necator), exhibiting both protectant and post-infective properties.

Carboxin (Standard) is the standard substance of Carboxin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Carboxin (Kisvax) appears as off-white crystals. Systemic fungicide and seed protectant.

Isoprothiolane (Standard) is the standard substance of Isoprothiolane, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Isoprothiolane is a foliar spray fungicide with eradicant and protectant activities against fungal diseases of rice plant caused by Pyvioutavia oryzae Cav.

Tadehaginoside, a phenylpropanoid glycoside, regulates adipogenesis and glucose consumption and possesses antioxidant properties. By modulating the Nrf2 and NF-κB signaling pathways in hepatic cells, Tadehaginoside acts as a liver protectant, preventing oxidative stress damage and inflammation. It is applicable in the study of obesity and diabetes.

Dexpramipexole ((R)-Pramipexole), a BTZ structural analog of riluzole, is a mitochondrial protectant that maintains mitochondrial function and energy production, attenuates myocardial ischemia/reperfusion injury by up-regulating mitochondrial autophagy, and can be used in the treatment of amyotrophic lateral sclerosis disease.