phosphatidyl choline

Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup. They are a major component of biological membranes and can be easily obtained from a variety of readily available sources, such as egg yolk or soybeans, from w

Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders. Exogenous administration of citicoline to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.

Phosphatidylcholines,soya (Soybean phosphatidylcholine) is a phosphatidylcholine from soybean used in the preparation of liposomes.

RHC 80267 (U-57908) is a selective inhibitor of DAGL, with an IC50 of 4 μM in canine platelets.

Lecithin (L-alpha-phosphatidylcholine) is considered a safe source of conventional phospholipids. Phospholipids can change the fatty acid composition and microstructure of animal cell membrane.

1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL) is a cylindrical-shaped lipid used to synthesize liposomes. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL) is the lipid component in the lipid nanoparticle (LNP) system.

1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid utilized in liposomes for the study of lipid monolayers and bilayers.

Palmitoyldocosahexaenoyl phosphatidylcholine is a polyunsaturated fatty acid that mimics special cell membrane structural domain lipids.

PGPC (1-Palmitoyl-2-glutaryl phosphatidylcholine) is an oxidized phospholipid and activates peroxisome proliferator-activated receptor in a concentration-dependent manner.

1,2-Didecanoyl-sn-glycero-3-phosphocholi (1,2-Didecanoyl PC) is a synthetic, less hydrophobic phospholipid that has been found to be useful for enhancing the absorption of peptide drugs and hormones such as insulin.

1-Palmitoyl-2-Linoleoyl-sn-glycero-3-phosphatidylcholine (PC) is a phospholipid characterized by the incorporation of palmitic (16:0) and linoleic (18:2) acids at the sn-1 and sn-2 positions, respectively. It is utilized in the creation of micelles, liposomes, and various artificial membranes, playing a significant role in research on lipid peroxidation.

1-Palmitoyl-2-lauroyl-sn-glycero-3-PC (1,2-PLPC) is a phospholipid with palmitoyl (16:0) and lauryl (12:0) acyl chains at the sn-1 and sn-2 positions, respectively. This mixed-chain phosphatidylcholine aids in researching the role of chain-chain contact interactions in maintaining the structural stability of lipid membrane bilayers.

Dihomo-γ-Linolenoyl PAF C-16 is a PAF analogue that incorporates dihomo-γ-linolenoate at the sn-2 position instead of the acetate moiety found in PAF C-16.

DL-α-Phosphatidylcholine, distearoyl is a synthetic form of phosphatidylcholine, that spontaneously forms bilayer membranes in aqueous environments. It is a vital component of biological membranes and supports cellular structural integrity. Additionally, DL-α-Phosphatidylcholine, distearoyl plays a crucial role in preparing compound delivery systems, enhancing solubility and biocompatibility of compounds.

1-(1(Z)-Hexadecenyl)-2-palmitoleoyl-sn-glycero-3-phosphocholine is a plasmalogen characterized by the presence of 1(Z)-hexadecenoic acid and palmitoleic acid located at the sn-1 and sn-2 positions, respectively.

L-α-Phosphatidylcholine β-(pyren-1-yl)hexanoyl-γ-palmitoyl is a reagent used in biochemical reactions.

GSK2194069 is an active β-keto reductase (KR)-specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released CoA.GSK2194069 inhibits the proliferation of FAS in cancer cells through the action of acetoacetyl-coenzyme A and NADPH.

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) is a phospholipid commonly found in cell membranes, with cholesterol compositions ranging from 0 to 60 mol%.

Hexadecenyl-2-hydroxy-sn-glycero-3-PC (C16(Plasm) LPC) is a phosphatidylcholine. It can extend the lag phase of α-synuclein aggregation, making it valuable for Parkinson's disease research.

Myristoyllysophosphatidylcholine is a bioactive chemical.

Lysophosphatidylcholines (Lyso-Lecithins (egg)) are orally active lipids that induce cell damage and apoptosis, and induce demyelination. Lysophosphatidylcholines play a role in mediating inflammation, fibrosis, and cancer, and can be used to study atherosclerosis.

Lysophosphatidylcholine 18:2 is a mouse metabolite functionally related to linoleic acid.18:2 LysoPC is a major component of oxidized low-density lipoproteins (LDLs), and low plasma levels of LPC 18:2 have been associated with metabolic disorders such as impaired glucose tolerance, insulin resistance, type 2 diabetes, and coronary artery disease.1-Linoleoyl 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC is also a substrate for the generation of lysophosphatidic acid (LPA) from Autotaxin (LysoPLD), which plays an important role in cell motility.

Lysophosphatidylcholine C19:0 (1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine), an acyl chain lipid, enhances IL-1beta secretion [1].

Hydrogenated soya phosphatidylcholines, a natural compound, enhances the controlled release of water-soluble drugs in oral drug delivery systems by improving drug loading and solubility [1].