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Results for "

ocular

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    103
    TargetMol | Inhibitors_Agonists
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    10
    TargetMol | Peptide_Products
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    TargetMol | Inhibitory_Antibodies
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    TargetMol | Inhibitors_Agonists
Omidenepag isopropyl
DE-117, DE117, DE 117
T163881187451-19-9In house
Omidenepag isopropyl (DE-117) is a selective prostaglandin EP2 receptor agonist and a novel topical ocular blood pressure lowering compound.Omidenepag isopropyl has a weak affinity for EP1, EP2, and FP receptors.Omidenepag isopropyl is used in studies of glaucoma and hypertension. Omidenepag isopropyl can be used to study glaucoma and hypertension.
  • Inquiry Price
8-10 weeks
Size
QTY
Bunazosin Hydrochloride
E-643, E643, E-1015, E 643, E 1015
T2692352712-76-2In house
Bunazosin Hydrochloride (E 1015) is an alpha(1)-adrenoceptor antagonist used as a systemic antihypertensive and an ocular hypotensive drug.
  • Inquiry Price
6-8 weeks
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Ot-730
QLT 091568
T68120870809-51-1In house
Ot-730(QLT 091568)is a novel selective beta-blocker prodrug for the study of ocular diseases.
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Ot-730 HCl
Ot-730 HCl(870809-51-1 Free base)
T68120L3026641-73-3In house
ot-730 HCl is a novel selective beta blocker prodrug for the study of ocular diseases.
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PG-11047 2HCl
PG-11047 2HCl(949933-50-0 Free base), CGC-11047 2HCl
T73400L In house
PG-11047 2HCl is an apoptosis-stimulating agent used in the treatment of genitourinary disorders, immune system disorders, genetic disorders and malformations, ocular disorders, and disorders of the blood and lymphatic systems, and in the study of lymphomas and prostate cancer.
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Tropicamide
Ro 1-7683
T12811508-75-4
Tropicamide (Ro 1-7683) is a synthetic muscarinic antagonist with anticholinergic properties similar to atropine. Upon ocular administration, it binds to and blocks muscarinic receptors in the sphincter and ciliary muscles, inhibiting cholinergic responses and causing pupil dilation and ciliary muscle paralysis. Tropicamide is used as a diagnostic agent to induce short-duration mydriasis and cycloplegia.
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Bromfenac sodium hydrate
Bromfenac sodium sesquihydrate, Bromfenac monosodium salt sesquihydrate
T2403120638-55-3
Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. Upon ophthalmic administration, bromfenac binds to and inhibits cyclooxygenase II (COX II), an enzyme that converts arachidonic acid to cyclic endoperoxides, which are prostaglandin (PG) precursors. By inhibiting PG formation, bromfenac prevents PG-induced inflammation, vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, increased vascular permeability, and elevated intraocular pressure (IOP).
  • Inquiry Price
7-10 days
Size
QTY
Difluprednate
Myser, Epitopic, CM 9155
T647223674-86-4
Difluprednate (Myser)(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.
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Emedastine
LY188695, Emadine
T397987233-61-2
Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its downstream activity. As a result this agent interferes with mediator release from mast cells either by inhibiting calcium ion influx across mast cell basophil plasma membrane or by inhibiting intracellular calcium ion release within the cells. In addition, emedastine may also inhibit the late-phase allergic reaction mediated through leukotrienes or prostaglandins, or by producing an anti-platelet activating factor effect. Upon ocular administration, emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva. Emedastine does not affect adrenergic, dopamine, or serotonin receptors.
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Brimonidine Tartrate
UK 14304 (tartrate), AGN190342 (tartrate), UK14304 tartrate, AGN190342 tartrate
T642270359-46-5
Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucoma or ocular hypertension.
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Diquafosol tetrasodium
INS365
T7423211427-08-6
Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film stability and visual function, as a topical treatment of dry eye disease.
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Tetrahydrozoline
Tetryzolin, Tetryzoline
T039784-22-0
Tetrahydrozoline (Tetryzoline), an alpha agonist, have an effect on the constriction of conjunctival blood vessels. This contributes to relieve the redness of the eye resulted from minor ocular irritants.
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Methyl-4-oxoretinoate
T7760038030-58-9
Methyl-4-oxoretinoate is a synthetic retinoid compound with anticancer compounds that can induce differentiation and apoptosis in cancer cells.Methyl-4-oxoretinoate is used in the treatment of acne, psoriasis, and other skin disorders.Methyl-4-oxoretinoate has the potential to be used in the treatment of a variety of ocular disorders such as age-related macular degeneration. related macular degeneration).
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Naphazoline nitrate
Benil,Sanorin Spofa,Rhinon,Rinazina,Clera
T0446L5144-52-5
Naphazoline nitrate is an α1-Adrenergic receptor agonist. It also induces autophagy and necrotic cell death in erythroleukemia cells and inhibits erythroid differentiation. It used to treat congestion and ocular pathologies.
  • Inquiry Price
7-10 days
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(E)-Alprenoxime
CDDD-1815
T10001125720-84-5
(E)-Alprenoxime, the isomer of Alprenoxime, is a site-activated ocular β-blocker.
  • Inquiry Price
6-8 weeks
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Bimatoprost D5
AGN 192024 D5
T10544
Bimatoprost (AGN 192024) D5 is a deuterium-labeled Bimatoprost. Bimatoprost is a topical hypotensive agent frequently used for treating glaucoma and ocular hypertension.
  • Inquiry Price
7-10 days
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Flavanone hydrazone
T112941692-46-2
Flavanone hydrazine is a potent non-steroidal anti-inflammatory agent that effectively inhibits lens protein–induced ocular inflammation.
  • Inquiry Price
2-4 weeks
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(Rac)-MGV354
MGV354
T126701852495-86-3
(Rac)-MGV354 (MGV354) is the racemate of MGV354. MGV354 is a soluble activator of guanylate cyclase (sGC)(EC50s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively).
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Unoprostone
T13955120373-36-6
Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension.
  • Inquiry Price
10-14 weeks
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Balapiravir
R1626,Ro 4588161
T14493690270-29-2
Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). IC50 Value: Target: HCV Balapiravir was discontinued for safety reasons in 28-36% of patients (m
  • Inquiry Price
7-10 days
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Latanoprostene bunod
NCX116, LBN
T15719860005-21-6
Latanoprostene bunod (LBN) is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT).
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Omidenepag
UR-7276
T163891187451-41-7
Omidenepag (UR-7276) is a selective and potent prostaglandin E2 receptor 2 (EP2) agonist and a novel topical ocular hypotensive agent.Omidenepag is used in the study of glaucoma and hypertension.
  • Inquiry Price
7-10 days
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levobetaxolol
(S)-Betaxolol, (S)-(-)-Betaxolol
T1968293221-48-8
Levobetaxolol, also known as AL-1577A and Betaxon, is a cardioselective β-adrenergic receptor inhibitor. It has been demonstrated to reduce intraocular pressure in patients affected by ocular hypertension and primary open-angle glaucoma.
  • Inquiry Price
1-2 weeks
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Ketorolac hydrochloride
RS37619 hydrochloride
T200526218934-99-7
Ketorolac (RS37619) hydrochloride is a nonsteroidal anti-inflammatory drug and a non-selective COX inhibitor, exhibiting IC50 values of 20 nM for COX-1 and 120 nM for COX-2. This compound is utilized in a 0.5% ophthalmic solution format for the investigation of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and post-operative ocular inflammation pain. Additionally, Ketorolac hydrochloride serves as a DDX3 inhibitor, making it pertinent for research in cancer therapies.
  • Inquiry Price
2-4 weeks
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