no 756

NO 756 is a D1 dopamine receptor antagonist.

K-756 is a direct and selective inhibitor of tankyrase (TNKS), inhibiting the ADP-ribosylation activity of TNKS1 [IC50 = 31 nM] and TNKS2 [IC50 = 36 nM].

TAK-756 is a TAK1 inhibitor that selectively targets IRAK1/4 and exhibits excellent intra-articular pharmacokinetic properties. TAK1 is a potential molecular target for osteoarthritis (OA) due to its complementary anti-catabolic and anti-inflammatory effects.

CRBN ligand-756 is an E3 ubiquitin ligase cereblon (CRBN) ligand designed to recruit cereblon proteins. By linking it to a target protein ligand, CRBN ligand-756 can form a PROTAC.

SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.

VB7-756 is an antibody targeting HER2/CD340 and can be used for oncology research.

Epetraborole R-Mandelate is a potent and selective leucyl-tRNA synthetase inhibitor.