mucin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1309	Gastric mucin		Antibacterial , Antibiotic
	Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma.		Antibacterial , Antibiotic
T38976	MUC1, mucin core	MUC1, mucin core
	MUC1, mucin core is a type I transmembrane glycoprotein that is characterized by its overexpression and abnormal glycosylation in carcinoma cells. It specifically binds to domain 1 of ICAM-1.
T4S0969	Obtusifolin		Antioxidant , NF-κB
	1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...		Antioxidant , NF-κB
T11668	IQB-782		Others
	IQB-782 is a mucolytic agent with mucolytic expectorant activity.IQB-782 inhibits thrombin-activating fibrinolytic inhibitor (TAFI), protects rats from tobacco smoke-induced respiratory obstruction, reduces the viscosity...		Others
T1481	Fudosteine		Others
	Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.		Others
T12282	Benzyl-α-GalNAc	O-glycosylation-IN-1	Others
	Benzyl-α-GalNAc (O-glycosylation-IN-1) is a potent inhibitor of O-glycosylation and is used to reduce mucin on cell surfaces.		Others
T4S0878	Prunetin	Prunusetin	ERK , Dehydrogenase , NF-κB
	1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...		ERK , Dehydrogenase , NF-κB
T3821	Deapioplatycodin D	Deapi-platycodin D,DesapioplatycodinD	Others , HCV Protease
	Deapioplatycodin D and platycodin D can regulate the production and secretion of airway mucin and, at least in part, explains the traditional use of aqueous extract of APG as expectorants in diverse inflammatory pulmonar...		Others , HCV Protease
TN2089	Platycodin D3		HCV Protease , NF-κB
	Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway mucin; it can significantly enhance mitogen- and OVA-induced...		HCV Protease , NF-κB
T2S2108	Coixol	6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA	Others , Antibacterial
	1. Coixol (MBOA) acts as a central muscle relaxant with an anti-convulsant effect. 2. Coixol interacts with the pituitary to stimulate reproduction in voles. 3. Coixol has the ability to interact with FSH to stimulate fo...		Others , Antibacterial
T4503	Talniflumate	Somalgen	Chloride channel , COX , N-Acetylglucosaminyltransferase , Anion Exchanger
	Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition o...
T3889	Platycodin D		Prostaglandin Receptor , AMPK
	Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 1...		Prostaglandin Receptor , AMPK
TP1834	MUC5AC motif peptide
	MUC5AC motif peptide is a 16-amino acid fragment of mucin 5.
T62125	Colistin adjuvant-1
	Colistin adjuvant-1 is a mucin adjuvant with enhanced mucin-enhancing activity against gram-negative bacteria. colistin adjuvant-1 exhibits inhibition of NF-κB (IC50: 0.209 μM).
T76967	Ubamatamab
	Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].
T78318	Gatipotuzumab	PankoMab
	Gatipotuzumab (PankoMab), a humanized monoclonal antibody, targets the tumor-specific epitope TA-MUC1 of mucin-1 and exhibits potent tumor-specific antibody-dependent cell cytotoxicity (ADCC) [1] [2].
T71286	Guaifenesin-d3
	Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin by GC- or LC-MS. Guaifenesin is an expectorant. It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and e...
T78334	Surzebiclimab	BGB-A425
	Surzebiclimab (BGB-A425), a humanized variant IgG1 monoclonal antibody, targets and binds with high affinity (K D = 0.36 nM) and specificity to the extracellular domain of T-cell immunoglobulin and mucin-domain containin...
TN1848	Kuwanon E		AChR
	Kuwanon E inhibited cholinesterase enzyme in a dose-dependent manner with K i values ranging between 3.1 and 37.5 μM and between 1.7 and 19.1 μM against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzyme...		AChR
T71143	Ambroxol-d5
	Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrica...