malt

Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.

Malt extract can serve as a nutritional source in culture media. It is applicable as a biomaterial or organic compound relevant to life science research.

MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor.

MALT1-IN-9 (WO2021000855A1, Compound 5), a highly potent inhibitor of MALT1 protease, demonstrates an IC50 value of <500 nM when tested in Raji MALT1-GloSensor cells. MALT1-IN-9 exhibits significant anticancer properties [1].

(S)-MALT1-IN-5 is a potent inhibitor of MALT1 protease, capable of inhibiting MALT1 activity and potentially mitigating the enhancement of MALT1 activity due to abnormal T-cell or B-cell receptor signaling, cancer, or inflammatory diseases. It has potential for studies related to MALT1-related diseases.

MALT1-IN-5 is a potent inhibitor of the MALT1 protease and can be used in cancer research.

MALT1-IN-8 is a potent inhibitor of MALT1 protease (IC50: 2 nM) that inhibits the growth of OCI-LY3 lymphoma cells (IC50: 1.16 μM) and exhibits anticancer activity.

(R)-MALT1-IN-3 (compound 121) is a potent MALT1 protease inhibitor with an IC50 of 20 nM, and demonstrates IC50 values of 60 nM and 40 nM for human IL6 and IL10, respectively, in OCI-LY3 cells.

MALT1-IN-3 is a potent inhibitor of MALT1 protease (IC50: 0.06 μM) with IC50 values of 0.14 and 0.13 μM for human IL6 and IL10, respectively, in OCI-LY3 cells.

(R)-MALT1-IN-7 (compound 142a) is a potent MALT1 protease inhibitor with potential applications in cancer research.

MALT1-IN-7 [compound 142b] is a potent MALT1 protease inhibitor with potential applications in cancer research.

MALT1-IN-6 is a MALT1 protease inhibitor (Ki: 9 nM) that exhibits anticancer activity.

MALT1-IN-11, a potent MALT1 protease inhibitor (IC 50 < 10 nM), effectively reduces IL10 secretion, exhibiting an IC 50 between 10-100 nM. This compound is primarily utilized in the study of cancer, autoimmune, and inflammatory disorders.

NVS-MALT1 is an allosteric inhibitor of MALT1 [1].

Maltose (maltobiose) is a reducing sugar and is a disaccharide formed from two units of glucose bound by a (1-4) bond. Maltose can be used as an energy source for bacteria.

D-(+)-Maltose monohydrate (D-(+)-Maltose monohydrate), a dextrodisaccharide from starch and malt, is used as a fermentable intermediate and sweetening agent in brewing.

Isomaltose (D-Isomaltose) is a reducing disaccharide, similar to maltose, but with an α-(1-6)-linkage instead of the α-(1-4)-linkage.

Maltitol (4-O-α-glucopyranosyl-D-sorbitol) is a sugar alcohol (polyol) used as a sugar substitute.

Ferric maltol (Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate) is a ferric, non-salt-based oral iron formulation demonstrating improved tolerance in patients with previous intolerance to other iron formulations.

N-Dodecyl-β-D-maltoside (Lauryl Maltoside) is an alkyl maltopyranoside detergent, particularly useful in transporters and respiratory complexes. It is a derivative of pyrene (Py) and has applications in the purification and stabilization of RNA polymerase, as well as the detection of protein-lipid interactions.

Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive, and orally active pan-PTP (protein tyrosine phosphatases) inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent insulin sensitizer and has been shown to improve cardiac dysfunctions in diabetic models. BMOV inhibits HCPTPA, PTP1B, HPTPβ, and SHP2 with IC50s of 126 nM, 109 nM, 26 nM, and 201 nM, respectively [1][2].

Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.

Maltotriose is an inducer of E. coli maltose regulator, the second most abundant sugar in brewing. It induces beta-galactosidase synthesis.

Maltol is a type of aromatic compound found in high concentrations in red ginseng and is a potent antioxidant used to enhance flavor and preserve food.