lymphoid

Phytohemagglutinin (PHA-M) is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3. Anti-tumor activity

1-beta-D-Arabinofuranosylthymine (Thymine 1-β-D-arabinofuranoside) is a purine nucleoside analog. Purine nucleoside analogs have a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing apoptosis.1-beta-D-Arabinofuranosylthymine's anticancer mechanism is dependent on the inhibition of DNA synthesis.1-beta-D-Arabinofuranosylthymine is a purine nucleoside analog.

Pladienolide B is a potent spliceosome inhibitor, a macrolide isolated from Streptomyces obtusususus Mer-12, which targets the SF3B1 subunit of the spliceosome.Pladienolide B exerts its antitumor effects by inhibiting pre-mRNA splicing and inducing necrosis.Pladienolide B possesses antitumor activity and can be used to study leukemia and lymphoid tumors. Pladienolide B has antitumor activity and can be used to study leukemia and lymphoid tumors.

Yadanzioside E is a natural product that inhibits HIV viral replication in the H9 T lymphoid cell line, and is widely used in biochemical experiments and drug synthesis research.

Phytohemagglutinin P (PHA-P) is a naturally occurring lectin, the protein form of PHA.PHA is a selective T-cell mitogen that binds T-cell receptors and enhances HIV-1 replication.

Piptocarphin A shows strong cytotoxic activity against mouse lymphoid tumor cell line P388 with the IC(50) value of 0.77 microM.

Piptocarphin F shows strong cytotoxic activities against mouse lymphoid tumor cell line P388. It also shows cytotoxic activity (IC50 3.87-12.5 umol/L) against the human leukemic cell line HL-60.

Bruceoside D is a quassinoid natural product discovered in Brucea javanica, exhibiting inhibitory activity against HIV replication in the H9 T-lymphoid cell line (IC50 = 3 μM) and demonstrating potential anticancer activity.

Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing apoptosis.The anticancer mechanism of Nebularine is dependent on the inhibition of DNA synthesis.